Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

troubleshoot failed executions #11

Open
wants to merge 1 commit into
base: main
Choose a base branch
from
Open

Conversation

mgonzalezporta
Copy link
Member

@mgonzalezporta mgonzalezporta commented Mar 29, 2022

Troubleshooting outcome:

  • 3/4 rescued (2 from aldy + 1 from cyrius)
  • 1/4 needs follow up with authors (1 from aldy)

@rodrigotoro Would you be able to help in raising a ticket for the failed sample? It may require follow up with access to CRAM files. The error message is as follows:

ERROR: gene= cyp2d6, profile= illumina, file= WHB4149.cram
Aldy could not phase any major solution.
Possible solutions:
 - Check the coverage. Extremely low coverage prevents Aldy from calling star-alleles.
 - Run with --debug parameter and notify the authors of Aldy.

The average coverage for this sample is 34X, so that's unlikely to be the issue. You can find the full logs to share with the authors here: s3://sg10k-cyp2d6-workspace/call_haplotypes/sg10k-dragen/outputs/WHB4149/aldy/.

Thanks!

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

Successfully merging this pull request may close these issues.

1 participant