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A tool for comparative genomics analysis that assesses the species relationship considering the phylogenetic distance provided by several gene trees.

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ELDOgraph - External Least Divergent Ortholog graph

Introduction:

ELDOgraph is a tool for comparative genomics analysis that 
assesses the species relationship considering the phylogenetic 
distance provided by several gene trees. 

Prerequisites:

Unix Platform;
PERL;
Internet connection;

For impatients:

> tar -zxvf ELDOgraph_vXXX.tgz
> cd eldograph
> ./eldograph_db -treedir <tree_directory> -taxtable <table_name> 
> ./eldograph_analayse -hashfile <hash_file> -rank <rank_code> 

For detailed description of ELDOgraph parameters:

> ./eldograph_db -man
> ./eldograph_analyse -man

Installation:

ELDOgraph is ready to use  in  most  of  Unix  Platform.  But  it  only 
works if the  folders  lib/  that follow this script are  in  the  same 
location. If you want to freely run ELDOgraph  in  other  location, add  
the ELDOgraph folder  into  the  environment  variable  by  using,  for 
example, the following commands:

> echo "export PATH=$PATH:/path/to/program/eldograph/" >> ~/.bash_profile
> source ~/.bash_profile

Running with sample files:

In the eldograph directory try the following commands
> ./eldograph_db -treedir sample_trees/ -taxtable sample_tax.tab -out sample_db.hash
> ./eldograph_analayse -hashfile sample_db.hash -rank genus -out sample_result

Outputs:

eldograph_db: a hash file containing the taxonomic and distance information.

eldograph_analyse:
  *.html:       a web page in which the results can be visualized in a graph
                structure.
  *.matrix.tab: a matrix containing the frequency of ELDO of a taxon with all 
                other taxon in the analysis
  *.tab:        same data as *.matrix.tab, but in 3-column-table.

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A tool for comparative genomics analysis that assesses the species relationship considering the phylogenetic distance provided by several gene trees.

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