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Link to cell reports methods paper (#37)
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LeonardSchmiester authored Mar 9, 2023
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Expand Up @@ -9,7 +9,7 @@ This package contains methods designed to determine the existance of
subpopulations with different responses to a given drug from a dataset of
screenings with that drug on the total cell population. The implementation is
based on the method presented in the article
["Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data"](https://doi.org/10.1101/2022.01.17.476604).
["Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data"](https://doi.org/10.1016/j.crmeth.2023.100417).
The dataset should contatin cell viability data tested on C different drug concentrations over
N time points and containing R replicates. The package can then estimate the
number of subpopulations, their mixture proportions and a dose-reponse curve
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