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Code used for the submitted manuscript (August 2019)

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Sequences of cognitive decline in typical Alzheimer’s disease and posterior cortical atrophy estimated using a novel event-based model of disease progression

This repo contains the code used for the manuscript: Firth et al., Alzheimer's and Dementia 2020

This is the Kernel Density Estimation (KDE) Event-Based Model (EBM).

Install the KDE EBM

Once inside this directly you can just install with pip using

pip install .

Scripts relevant to the paper

In the folder kde_ebm_paper you'll find scripts to generate synthetic data, the figures, and the related analyses in Firth et al., Alzheimer's and Dementia 2020.

Dependencies

The code depends heavily on NumPy, uses SciPy to calculate some stats and do some optimisation, uses Matplotlib just to do the plotting, and used scikit-learn for Kernel Density Estimation

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Code used for the submitted manuscript (August 2019)

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  • Python 97.8%
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