Sequences of cognitive decline in typical Alzheimer’s disease and posterior cortical atrophy estimated using a novel event-based model of disease progression
This repo contains the code used for the manuscript: Firth et al., Alzheimer's and Dementia 2020
This is the Kernel Density Estimation (KDE) Event-Based Model (EBM).
Once inside this directly you can just install with pip
using
pip install .
In the folder kde_ebm_paper
you'll find scripts to generate synthetic data, the figures, and the related analyses in Firth et al., Alzheimer's and Dementia 2020.
The code depends heavily on NumPy, uses SciPy to calculate some stats and do some optimisation, uses Matplotlib just to do the plotting, and used scikit-learn for Kernel Density Estimation