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Visualization
In the results.dir
you can find plots showing the MCPs' expression, composition, and phenotype-specific distributions as shown here for the ulcerative colitis MCP we identified (Jerby-Arnon and Regev, Nature Biotechnology 2022).
In the plot below each dot corresponds to a sample, showing the expression level of one MCP component as a function of another MCP component, together with the Pearson correlation coefficient:
The plot below shows the number of genes in the cell-type-specific and non-specific components of each MCP:
In case there is a specific feature or phenotype of interest DIALOGUE will plot the MCP expression when stratifying the cells according to that classification:
here, for example, we can see that the MCP identified in colon samples is higher in the disease state (UC).