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# Instructions | ||
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Calculate the Hamming Distance between two DNA strands. | ||
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Your body is made up of cells that contain DNA. | ||
Those cells regularly wear out and need replacing, which they achieve by dividing into daughter cells. | ||
In fact, the average human body experiences about 10 quadrillion cell divisions in a lifetime! | ||
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When cells divide, their DNA replicates too. | ||
Sometimes during this process mistakes happen and single pieces of DNA get encoded with the incorrect information. | ||
If we compare two strands of DNA and count the differences between them we can see how many mistakes occurred. | ||
This is known as the "Hamming Distance". | ||
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We read DNA using the letters C,A,G and T. | ||
Two strands might look like this: | ||
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GAGCCTACTAACGGGAT | ||
CATCGTAATGACGGCCT | ||
^ ^ ^ ^ ^ ^^ | ||
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They have 7 differences, and therefore the Hamming Distance is 7. | ||
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The Hamming Distance is useful for lots of things in science, not just biology, so it's a nice phrase to be familiar with :) | ||
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## Implementation notes | ||
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The Hamming distance is only defined for sequences of equal length, so an attempt to calculate it between sequences of different lengths should not work. |
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{ | ||
"authors": [ | ||
"glaxxie" | ||
], | ||
"files": { | ||
"solution": [ | ||
"hamming.gd" | ||
], | ||
"test": [ | ||
"hamming_test.gd" | ||
], | ||
"example": [ | ||
".meta/example.gd" | ||
] | ||
}, | ||
"blurb": "Calculate the Hamming difference between two DNA strands.", | ||
"source": "The Calculating Point Mutations problem at Rosalind", | ||
"source_url": "https://rosalind.info/problems/hamm/" | ||
} |
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func distance(strand_1, strand_2): | ||
var dist = 0 | ||
for i in range(len(strand_1)): | ||
if strand_1[i] != strand_2[i]: | ||
dist += 1 | ||
return dist |
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# This is an auto-generated file. | ||
# | ||
# Regenerating this file via `configlet sync` will: | ||
# - Recreate every `description` key/value pair | ||
# - Recreate every `reimplements` key/value pair, where they exist in problem-specifications | ||
# - Remove any `include = true` key/value pair (an omitted `include` key implies inclusion) | ||
# - Preserve any other key/value pair | ||
# | ||
# As user-added comments (using the # character) will be removed when this file | ||
# is regenerated, comments can be added via a `comment` key. | ||
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[f6dcb64f-03b0-4b60-81b1-3c9dbf47e887] | ||
description = "empty strands" | ||
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[54681314-eee2-439a-9db0-b0636c656156] | ||
description = "single letter identical strands" | ||
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[294479a3-a4c8-478f-8d63-6209815a827b] | ||
description = "single letter different strands" | ||
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[9aed5f34-5693-4344-9b31-40c692fb5592] | ||
description = "long identical strands" | ||
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[cd2273a5-c576-46c8-a52b-dee251c3e6e5] | ||
description = "long different strands" | ||
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[919f8ef0-b767-4d1b-8516-6379d07fcb28] | ||
description = "disallow first strand longer" | ||
include = false | ||
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[b9228bb1-465f-4141-b40f-1f99812de5a8] | ||
description = "disallow first strand longer" | ||
reimplements = "919f8ef0-b767-4d1b-8516-6379d07fcb28" | ||
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[8a2d4ed0-ead5-4fdd-924d-27c4cf56e60e] | ||
description = "disallow second strand longer" | ||
include = false | ||
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[dab38838-26bb-4fff-acbe-3b0a9bfeba2d] | ||
description = "disallow second strand longer" | ||
reimplements = "8a2d4ed0-ead5-4fdd-924d-27c4cf56e60e" | ||
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[5dce058b-28d4-4ca7-aa64-adfe4e17784c] | ||
description = "disallow left empty strand" | ||
include = false | ||
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[db92e77e-7c72-499d-8fe6-9354d2bfd504] | ||
description = "disallow left empty strand" | ||
include = false | ||
reimplements = "5dce058b-28d4-4ca7-aa64-adfe4e17784c" | ||
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[b764d47c-83ff-4de2-ab10-6cfe4b15c0f3] | ||
description = "disallow empty first strand" | ||
reimplements = "db92e77e-7c72-499d-8fe6-9354d2bfd504" | ||
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[38826d4b-16fb-4639-ac3e-ba027dec8b5f] | ||
description = "disallow right empty strand" | ||
include = false | ||
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[920cd6e3-18f4-4143-b6b8-74270bb8f8a3] | ||
description = "disallow right empty strand" | ||
include = false | ||
reimplements = "38826d4b-16fb-4639-ac3e-ba027dec8b5f" | ||
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[9ab9262f-3521-4191-81f5-0ed184a5aa89] | ||
description = "disallow empty second strand" | ||
reimplements = "920cd6e3-18f4-4143-b6b8-74270bb8f8a3" |
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func distance(strand_1, strand_2): | ||
pass |
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func test_empty_strands(solution_script): | ||
var values = ["", ""] | ||
var expected = 0 | ||
return [solution_script.distance(values[0], values[1]), expected] | ||
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func test_single_letter_identical_strands(solution_script): | ||
var values = ["A", "A"] | ||
var expected = 0 | ||
return [solution_script.distance(values[0], values[1]), expected] | ||
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func test_single_letter_different_strands(solution_script): | ||
var values = ["G", "T"] | ||
var expected = 1 | ||
return [solution_script.distance(values[0], values[1]), expected] | ||
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func test_long_identical_strands(solution_script): | ||
var values = ["GGACTGAAATCTG", "GGACTGAAATCTG"] | ||
var expected = 0 | ||
return [solution_script.distance(values[0], values[1]), expected] | ||
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func test_long_different_strands(solution_script): | ||
var values = ["GGACGGATTCTG", "AGGACGGATTCT"] | ||
var expected = 9 | ||
return [solution_script.distance(values[0], values[1]), expected] | ||
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