This repository contains R code which was used to study the expression of a metabolic injury signature discovered in mice in a human Crohn's Disease cohort. Two R notebooks are included:
- ibd_prediction.Rmd: Compares the expression patterns of the signature between humans and mice
- DEG Analysis.Rmd: Contains a differential expression analysis for the human data, highlighting the signature genes
Clone the repository:
https://github.com/biomedbigdata/gene_signatures.git
Navigate to the directory:
cd gene_signatures
Install dependencies by opening an R session and running:
renv::install()
Run the R notebooks, e.g. with RStudio.