SlicerRt use cases

Dose accumulation and its evaluation by DVH

Source: Michele Avanzo (Centro di Riferimento Oncologico di Aviano)

• Load first phase (planning) CT, dose and structures
• Load second phase CT and dose
• B-Spline image registration of the first and second phase CT images
• Resample second phase dose distribution using the result transformation (having first phase dose as reference)
• Accumulate the first phase dose with the transformed second phase dose in a weighted manner (3.125 and 2.667, respectively)
• Compute DVH for the target and OARs using the accumulated dose distribution

Proton dose calculation

Source: Greg Sharp (MGH)

• Import CT and structure sets
• Create and configure beams
• Calculate proton dose
• Export plan to treatment machine

Computation of accumulated dose

Source: Young-Bin Cho, Seungjong Oh (PMH)

• Import CT images and dose maps from DICOM-RT
• Compute the transform corresponding to target dislocation/deformation from image registration
• Apply the transform to dose map
• Sum the dose values in the registered data sets

Evaluation of gel dosimetry

Source: John Schreiner, Matthew Marsh, Kevin Alexander (KGH)

• Loading a planning image and a planned dose distribution
• Load an on-board imager cone beam CT
• Register CBCT to planning CT
• Load a 3D optical CT scan of the gel, or a 2D scan of the film (measured). Format is 3D vff or a 2D picture format (eg. tiff, could be grayscale or RGB)
• Register measured image to CBCT using fiducial marks
• Apply dose calibration curves (arbitrary scalar math operations) to measured image, yielding measured dose
• Perform a gamma, chi, etc. test between measured dose and planned dose, yielding comparison volume
• Extract statistics from comparison volume

MRI-US fusion for prostate brachytherapy

Source: Cynthia Menard (CHUM, Montreal)

• Import MRI and US studies
• Register the prostate structure with deformable registration
• Apply transformation on whole MRI study
• Export deformed study to DICOM-RT

Testing of treatment planning algorithms

Source: Dionne M. Aleman (UofT)

• Import CT images, structure sets, and dose maps from DICOM-RT
• Convert data into usable data structures
• Perform treatment planning optimization
• Plot DVHs
• Plot colorwash+isodose lines for all image slices
• Calculate conformity indices
• Do all these in a batch mode on a large amount of data (without user interaction).

Evaluation of deformable registration on delivered dose

Source: Sunnybrook (Lee Chin)

• Import CT image, dose map, and structure sets from DICOM-RT
• Compute the transform corresponding to target dislocation/deformation from image registration
• Apply the transform to structure sets (the outputs are also contour objects)
• Compare the DVH of the dose for the original and the transformed structure sets
• Perform Dice and Hausdorff contour comparison
• Export the deformed contours to DICOM-RT

Additional supported use cases

• External Beam Planning: Calculate dose using arbitrary dose computation engines implemented in a variety of languages including Matlab
• Image-Guided Radiation Therapy: calculation and export of the daily couch shift/rotation
• Collision detection: simulate treatment machine geometry and replay plan delivery
• Film dosimetry
• Orthovoltage RT of skin lesions
• Batch processing: Conversion of DICOM-RT objects into non-DICOM files; Resampling, structure representation conversion, other processing
• Calculation of target structure margins
• Treatment plan approximation from database of plans