diff --git a/scripts/pylib/twister/twisterlib/handlers.py b/scripts/pylib/twister/twisterlib/handlers.py
index aeb252f872060f..9ec0eade2153ca 100755
--- a/scripts/pylib/twister/twisterlib/handlers.py
+++ b/scripts/pylib/twister/twisterlib/handlers.py
@@ -460,14 +460,20 @@ def monitor_serial(self, ser, halt_event, harness):
     def device_is_available(self, instance):
         device = instance.platform.name
         fixture = instance.testsuite.harness_config.get("fixture")
-        dut_found = False
+        duts_found = []
 
         for d in self.duts:
             if fixture and fixture not in map(lambda f: f.split(sep=':')[0], d.fixtures):
                 continue
             if d.platform != device or (d.serial is None and d.serial_pty is None):
                 continue
-            dut_found = True
+            duts_found.append(d)
+
+        if not duts_found:
+            raise TwisterException(f"No device to serve as {device} platform.")
+
+        # Select an available DUT with less failures
+        for d in sorted(duts_found, key=lambda _dut: _dut.failures):
             d.lock.acquire()
             avail = False
             if d.available:
@@ -480,9 +486,6 @@ def device_is_available(self, instance):
             if avail:
                 return d
 
-        if not dut_found:
-            raise TwisterException(f"No device to serve as {device} platform.")
-
         return None
 
     def make_dut_available(self, dut):
diff --git a/scripts/tests/twister/test_handlers.py b/scripts/tests/twister/test_handlers.py
index ec4db7859c5804..b857ae3cc20a48 100644
--- a/scripts/tests/twister/test_handlers.py
+++ b/scripts/tests/twister/test_handlers.py
@@ -738,6 +738,7 @@ def test_devicehandler_monitor_serial(
                 fixtures=[],
                 platform='dummy_platform',
                 available=1,
+                failures=0,
                 counter_increment=mock.Mock(),
                 counter=0
             ),
@@ -745,6 +746,7 @@ def test_devicehandler_monitor_serial(
                 fixtures=['dummy fixture'],
                 platform='another_platform',
                 available=1,
+                failures=0,
                 counter_increment=mock.Mock(),
                 counter=0
             ),
@@ -754,6 +756,7 @@ def test_devicehandler_monitor_serial(
                 serial_pty=None,
                 serial=None,
                 available=1,
+                failures=0,
                 counter_increment=mock.Mock(),
                 counter=0
             ),
@@ -762,12 +765,73 @@ def test_devicehandler_monitor_serial(
                 platform='dummy_platform',
                 serial_pty=mock.Mock(),
                 available=1,
+                failures=0,
+                counter_increment=mock.Mock(),
+                counter=0
+            ),
+            mock.Mock(
+                fixtures=['dummy fixture'],
+                platform='dummy_platform',
+                serial_pty=mock.Mock(),
+                available=1,
+                failures=0,
                 counter_increment=mock.Mock(),
                 counter=0
             )
         ],
         3
     ),
+    (
+        'dummy_platform',
+        'dummy fixture',
+        [
+            mock.Mock(
+                fixtures=[],
+                platform='dummy_platform',
+                available=1,
+                failures=0,
+                counter_increment=mock.Mock(),
+                counter=0
+            ),
+            mock.Mock(
+                fixtures=['dummy fixture'],
+                platform='another_platform',
+                available=1,
+                failures=0,
+                counter_increment=mock.Mock(),
+                counter=0
+            ),
+            mock.Mock(
+                fixtures=['dummy fixture'],
+                platform='dummy_platform',
+                serial_pty=None,
+                serial=None,
+                available=1,
+                failures=0,
+                counter_increment=mock.Mock(),
+                counter=0
+            ),
+            mock.Mock(
+                fixtures=['dummy fixture'],
+                platform='dummy_platform',
+                serial_pty=mock.Mock(),
+                available=1,
+                failures=1,
+                counter_increment=mock.Mock(),
+                counter=0
+            ),
+            mock.Mock(
+                fixtures=['dummy fixture'],
+                platform='dummy_platform',
+                serial_pty=mock.Mock(),
+                available=1,
+                failures=0,
+                counter_increment=mock.Mock(),
+                counter=0
+            )
+        ],
+        4
+    ),
     (
         'dummy_platform',
         'dummy fixture',
@@ -783,6 +847,7 @@ def test_devicehandler_monitor_serial(
                 platform='dummy_platform',
                 serial_pty=mock.Mock(),
                 counter_increment=mock.Mock(),
+                failures=0,
                 available=0
             ),
             mock.Mock(
@@ -790,6 +855,7 @@ def test_devicehandler_monitor_serial(
                 platform='dummy_platform',
                 serial_pty=mock.Mock(),
                 counter_increment=mock.Mock(),
+                failures=0,
                 available=0
             ),
             mock.Mock(
@@ -797,6 +863,7 @@ def test_devicehandler_monitor_serial(
                 platform='dummy_platform',
                 serial=mock.Mock(),
                 counter_increment=mock.Mock(),
+                failures=0,
                 available=0
             ),
             mock.Mock(
@@ -804,6 +871,7 @@ def test_devicehandler_monitor_serial(
                 platform='dummy_platform',
                 serial=mock.Mock(),
                 counter_increment=mock.Mock(),
+                failures=0,
                 available=0
             )
         ],
@@ -814,7 +882,9 @@ def test_devicehandler_monitor_serial(
 @pytest.mark.parametrize(
     'platform_name, fixture, duts, expected',
     TESTDATA_10,
-    ids=['one good dut', 'exception - no duts', 'no available duts']
+    ids=['two good duts, select the first one',
+         'two duts, the first was failed once, select the second not failed',
+         'exception - no duts', 'no available duts']
 )
 def test_devicehandler_device_is_available(
     mocked_instance,