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somatic wgs does not include gnomad filtering #48

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chrisamiller opened this issue May 13, 2022 · 1 comment
Open

somatic wgs does not include gnomad filtering #48

chrisamiller opened this issue May 13, 2022 · 1 comment
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enhancement New feature or request

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@chrisamiller
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we use it in exome, in the filter_vcf step, but the gnomad vcf we're using is only a subset, restricted to exome coords. Would be nice to revisit that decision at some point (options: leave it out, apply it to exome only, or find a new genome-wide VCF)

@malachig
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presumably we can now get a genome-wide VCF from GNOMAD v3 which would seem a good solution here.

@malachig malachig added the enhancement New feature or request label Mar 24, 2023
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