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GroupRegNet

Implementation of GroupRegNet: A Groupwise One-shot Deep Learning-based 4D Image Registration Method. Zhang, Y., Wu, X., Gach, H. M., Li, H. H., & Yang, D. (2021). GroupRegNet: a groupwise one-shot deep learning-based 4D image registration method. Physics in Medicine & Biology.

GroupRegNet is an unsupervised deep learning-based DIR method that employs both groupwise registration and one-shot strategy to register 4D medical images and then to determine all pairwise deformation vector fields (DVFs).

Requirement

  • PyTorch
  • SimpleITK: read mhd files
  • logging and tqdm

Usage

To evaluate GroupRegNet with registration_dirlab.py, the DIR-Lab dataset is required. The original data needs to be converted into mhd format.

To convert the original landmark of Landmark300 and LandmarkDense, run convert_landmark_dirlab300.py and convert_landmark_dense.py.

Overall structure

groupreg_flowchart

Result

res_1

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res_3

Sizes, shapes, and locations of the contoured tumor targets, shown in violet shade, in coronal views of the EI phases of three patient cases. res_4

Comparison of the tracked targets in ten phases by GroupRegNet and manual contouring of case 1 and 3. The images are shown in coronal views, and the horizontal line in each figure is at the same height for visual reference. res_5

res_6