diff --git a/packages/app/src/App.tsx b/packages/app/src/App.tsx
index ac95ca561..b30c07afb 100644
--- a/packages/app/src/App.tsx
+++ b/packages/app/src/App.tsx
@@ -1,7 +1,7 @@
 import { assertAbsolutePath } from '@h5web/shared';
-import { useState, Suspense } from 'react';
+import { Suspense, useContext, useState } from 'react';
 import { ErrorBoundary } from 'react-error-boundary';
-import { ReflexContainer, ReflexSplitter, ReflexElement } from 'react-reflex';
+import { ReflexContainer, ReflexElement, ReflexSplitter } from 'react-reflex';
 
 import styles from './App.module.css';
 import ErrorFallback from './ErrorFallback';
@@ -10,6 +10,7 @@ import VisConfigProvider from './VisConfigProvider';
 import BreadcrumbsBar from './breadcrumbs/BreadcrumbsBar';
 import Explorer from './explorer/Explorer';
 import MetadataViewer from './metadata-viewer/MetadataViewer';
+import { ProviderContext } from './providers/context';
 import Visualizer from './visualizer/Visualizer';
 
 const DEFAULT_PATH = process.env.REACT_APP_DEFAULT_PATH || '/';
@@ -25,6 +26,13 @@ function App(props: Props) {
   const [isExplorerOpen, setExplorerOpen] = useState(!startFullscreen);
   const [isInspecting, setInspecting] = useState(false);
 
+  const { valuesStore } = useContext(ProviderContext);
+  function onSelectPath(path: string) {
+    setSelectedPath(path);
+    valuesStore.cancelOngoing();
+    valuesStore.evictCancelled();
+  }
+
   return (
     <ReflexContainer className={styles.root} orientation="vertical">
       <ErrorBoundary FallbackComponent={ErrorFallback}>
@@ -34,7 +42,7 @@ function App(props: Props) {
           flex={25}
           minSize={150}
         >
-          <Explorer selectedPath={selectedPath} onSelect={setSelectedPath} />
+          <Explorer selectedPath={selectedPath} onSelect={onSelectPath} />
         </ReflexElement>
 
         <ReflexSplitter
@@ -49,7 +57,7 @@ function App(props: Props) {
             isInspecting={isInspecting}
             onToggleExplorer={() => setExplorerOpen(!isExplorerOpen)}
             onChangeInspecting={setInspecting}
-            onSelectPath={setSelectedPath}
+            onSelectPath={onSelectPath}
           />
           <VisConfigProvider>
             <ErrorBoundary
@@ -62,7 +70,7 @@ function App(props: Props) {
                 {isInspecting ? (
                   <MetadataViewer
                     path={selectedPath}
-                    onSelectPath={setSelectedPath}
+                    onSelectPath={onSelectPath}
                   />
                 ) : (
                   <Visualizer path={selectedPath} />
diff --git a/packages/app/src/__tests__/Visualizer.test.tsx b/packages/app/src/__tests__/Visualizer.test.tsx
index e50969295..fb68d7e20 100644
--- a/packages/app/src/__tests__/Visualizer.test.tsx
+++ b/packages/app/src/__tests__/Visualizer.test.tsx
@@ -195,3 +195,60 @@ test('retry fetching dataset slice automatically when re-selecting slice', async
   jest.runOnlyPendingTimers();
   jest.useRealTimers();
 });
+
+test('cancel fetching dataset slice when changing entity', async () => {
+  jest.useFakeTimers('modern');
+  await renderApp();
+
+  // Select dataset and start fetching first slice
+  await selectExplorerNode('resilience/slow_slicing');
+  expect(await screen.findByText(/Loading current slice/)).toBeVisible();
+
+  // Switch to another entity to cancel the fetch
+  await selectExplorerNode('resilience/slow_value');
+  expect(await screen.findByText(/Loading data/)).toBeVisible();
+
+  // Let pending requests succeed
+  jest.runAllTimers();
+
+  // Reselect dataset and check that it refetches the first slice
+  await selectExplorerNode('resilience/slow_slicing');
+  // The slice request was cancelled so it should be pending once again
+  expect(await screen.findByText(/Loading current slice/)).toBeVisible();
+
+  // Let fetch of first slice succeed
+  jest.runAllTimers();
+  expect(await screen.findByRole('figure')).toBeVisible();
+
+  jest.runOnlyPendingTimers();
+  jest.useRealTimers();
+});
+
+test('cancel fetching dataset slice when changing vis', async () => {
+  jest.useFakeTimers('modern');
+  await renderApp();
+
+  // Select dataset and start fetching the slice
+  await selectExplorerNode('resilience/slow_slicing');
+  expect(await screen.findByText(/Loading current slice/)).toBeVisible();
+
+  // Switch to the Line vis to cancel the fetch
+  userEvent.click(screen.getByRole('tab', { name: 'Line' }));
+  expect(await screen.findByText(/Loading current slice/)).toBeVisible();
+
+  // Let pending requests succeed
+  jest.runAllTimers();
+  expect(await screen.findByRole('figure')).toBeVisible();
+
+  // Switch back to Heatmap and check that it refetches the slice
+  userEvent.click(screen.getByRole('tab', { name: 'Heatmap' }));
+  // The slice request was cancelled so it should be pending once again
+  expect(await screen.findByText(/Loading current slice/)).toBeVisible();
+
+  // Let fetch of the slice succeed
+  jest.runAllTimers();
+  expect(await screen.findByRole('figure')).toBeVisible();
+
+  jest.runOnlyPendingTimers();
+  jest.useRealTimers();
+});
diff --git a/packages/app/src/visualizer/VisManager.tsx b/packages/app/src/visualizer/VisManager.tsx
index 418933c36..f60ad59d3 100644
--- a/packages/app/src/visualizer/VisManager.tsx
+++ b/packages/app/src/visualizer/VisManager.tsx
@@ -1,8 +1,9 @@
 import type { Entity } from '@h5web/shared';
 import { assertDefined } from '@h5web/shared';
-import { useState } from 'react';
+import { useContext, useState } from 'react';
 
 import Profiler from '../Profiler';
+import { ProviderContext } from '../providers/context';
 import type { VisDef } from '../vis-packs/models';
 import VisSelector from './VisSelector';
 import styles from './Visualizer.module.css';
@@ -28,6 +29,13 @@ function VisManager(props: Props) {
 
   const [visBarElem, setVisBarElem] = useState<HTMLDivElement>();
 
+  const { valuesStore } = useContext(ProviderContext);
+  function onVisChange(vis: VisDef) {
+    setActiveVis(vis);
+    valuesStore.cancelOngoing();
+    valuesStore.evictCancelled();
+  }
+
   return (
     <div className={styles.visManager}>
       <div
@@ -37,7 +45,7 @@ function VisManager(props: Props) {
         <VisSelector
           activeVis={activeVis}
           choices={supportedVis}
-          onChange={setActiveVis}
+          onChange={onVisChange}
         />
       </div>