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DESCRIPTION
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DESCRIPTION
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Package: signals
Title: Single Cell Genomes with Allele Specificity
Version: 0.11.1
Author@R: c(person("Marc", "Williams", email = "[email protected]",
role = c("aut", "cre")),
person("Tyler", "Funnell",
role = c("cbt")))
Author: Marc J Williams [aut, cre],
Tyler Funnell [ctb]
Maintainer: Marc J Williams <[email protected]>
Description: signals (SIngle cell Genomes with Allele Specificity)
is a tool to estimate allele and haplotype specific copy number states in single cells with low coverage (~0.01X).
signals phases alleles based on losses and gains across all cells and then assigns allele specific states for each bin
in each cell using a hidden markov model.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
LazyDataCompression: xz
Depends:
R (>= 3.5.0)
biocViews:
Imports:
data.table,
magrittr,
dplyr,
uwot,
dbscan,
gtools,
forcats,
ComplexHeatmap,
GenomicRanges,
cowplot,
ape,
RColorBrewer,
tidyr,
ggplot2,
S4Vectors,
scales,
Rcpp,
ggrepel,
grid,
ggforce,
ggtree
RoxygenNote: 7.3.1
Suggests:
knitr,
rmarkdown,
markdown,
testthat (>= 2.1.0),
VGAM,
covr,
ggrastr,
VIBER,
Seurat,
plyranges
Remotes:
caravagnalab/easypar,
caravagnalab/VIBER
VignetteBuilder: knitr
LinkingTo:
Rcpp