diff --git a/Cargo.lock b/Cargo.lock
index b8bd2da..d029c41 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -723,24 +723,10 @@ checksum = "9a3a5bfb195931eeb336b2a7b4d761daec841b97f947d34394601737a7bba5e4"
 
 [[package]]
 name = "indoc"
-version = "0.3.6"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "47741a8bc60fb26eb8d6e0238bbb26d8575ff623fdc97b1a2c00c050b9684ed8"
-dependencies = [
- "indoc-impl",
- "proc-macro-hack",
-]
-
-[[package]]
-name = "indoc-impl"
-version = "0.3.6"
+version = "1.0.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ce046d161f000fffde5f432a0d034d0341dc152643b2598ed5bfce44c4f3a8f0"
+checksum = "e7906a9fababaeacb774f72410e497a1d18de916322e33797bb2cd29baa23c9e"
 dependencies = [
- "proc-macro-hack",
- "proc-macro2",
- "quote",
- "syn",
  "unindent",
 ]
 
@@ -998,25 +984,6 @@ dependencies = [
  "windows-sys",
 ]
 
-[[package]]
-name = "paste"
-version = "0.1.18"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "45ca20c77d80be666aef2b45486da86238fabe33e38306bd3118fe4af33fa880"
-dependencies = [
- "paste-impl",
- "proc-macro-hack",
-]
-
-[[package]]
-name = "paste-impl"
-version = "0.1.18"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d95a7db200b97ef370c8e6de0088252f7e0dfff7d047a28528e47456c0fc98b6"
-dependencies = [
- "proc-macro-hack",
-]
-
 [[package]]
 name = "pbkdf2"
 version = "0.10.1"
@@ -1057,12 +1024,6 @@ dependencies = [
  "toml",
 ]
 
-[[package]]
-name = "proc-macro-hack"
-version = "0.5.19"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "dbf0c48bc1d91375ae5c3cd81e3722dff1abcf81a30960240640d223f59fe0e5"
-
 [[package]]
 name = "proc-macro2"
 version = "1.0.36"
@@ -1107,35 +1068,46 @@ dependencies = [
 
 [[package]]
 name = "pyo3"
-version = "0.15.1"
+version = "0.16.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "7cf01dbf1c05af0a14c7779ed6f3aa9deac9c3419606ac9de537a2d649005720"
+checksum = "c00e5e97bb258ac0fcea67da5e845aae5f7e6fb4f723ec94a503a6d0a541ccb7"
 dependencies = [
  "cfg-if",
  "indoc",
  "libc",
  "parking_lot 0.11.2",
- "paste",
  "pyo3-build-config",
+ "pyo3-ffi",
  "pyo3-macros",
  "unindent",
 ]
 
 [[package]]
 name = "pyo3-build-config"
-version = "0.15.1"
+version = "0.16.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "dbf9e4d128bfbddc898ad3409900080d8d5095c379632fbbfbb9c8cfb1fb852b"
+checksum = "f61cb87bf5c9503fa0e7f38bcd311b31993328a5e29f3507dfbf763c8ccd37f4"
 dependencies = [
  "once_cell",
 ]
 
+[[package]]
+name = "pyo3-ffi"
+version = "0.16.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "5dd4b0b76ae07ca5a7b0527a75afc9f47744d14f4f3576bdf66a9a2420b5c54d"
+dependencies = [
+ "libc",
+ "pyo3-build-config",
+]
+
 [[package]]
 name = "pyo3-macros"
-version = "0.15.1"
+version = "0.16.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "67701eb32b1f9a9722b4bc54b548ff9d7ebfded011c12daece7b9063be1fd755"
+checksum = "a845f73eda2aa27d35b3840e2c6f0c9447347cdb49954552f09ae7b1f432a3d9"
 dependencies = [
+ "proc-macro2",
  "pyo3-macros-backend",
  "quote",
  "syn",
@@ -1143,9 +1115,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-macros-backend"
-version = "0.15.1"
+version = "0.16.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f44f09e825ee49a105f2c7b23ebee50886a9aee0746f4dd5a704138a64b0218a"
+checksum = "4e72ef79ca96c2dcb66d9b22f149400ac6c6b32ab468398ebbcb145d72f80c00"
 dependencies = [
  "proc-macro2",
  "pyo3-build-config",
diff --git a/stable-swap-math/sim/Cargo.toml b/stable-swap-math/sim/Cargo.toml
index e5d5645..0d61ec0 100644
--- a/stable-swap-math/sim/Cargo.toml
+++ b/stable-swap-math/sim/Cargo.toml
@@ -13,4 +13,4 @@ keywords = ["solana", "saber", "curve", "sim"]
 name = "sim"
 
 [dependencies]
-pyo3 = { version = "^0.15.1", features = ["auto-initialize"] }
+pyo3 = { version = "^0.16.1", features = ["auto-initialize"] }