diff --git a/librz/util/meson.build b/librz/util/meson.build
index eccbfa7f1fa..f7a9ca31704 100644
--- a/librz/util/meson.build
+++ b/librz/util/meson.build
@@ -147,7 +147,7 @@ if meson.is_cross_build()
       cc_native.find_library('psapi'),
     ]
   endif
-  rz_util_native_deps = [ldl_native, lrt_native, mth_native, th_native, utl_native, pcre2_dep] + platform_native_deps
+  rz_util_native_deps = [ldl_native, lrt_native, mth_native, th_native, utl_native, pcre2_native_dep] + platform_native_deps
   if execinfo_native.found()
     rz_util_native_deps += [execinfo_native]
   endif
diff --git a/meson.build b/meson.build
index a55a9e0b50e..c9f7c75b9da 100644
--- a/meson.build
+++ b/meson.build
@@ -204,13 +204,17 @@ endif
 
 pcre2_dep_opt = get_option('use_sys_pcre2')
 pcre2_dep = disabler()
-if pcre2_dep_opt.enabled() or pcre2_dep_opt.auto()
+if (pcre2_dep_opt.enabled() or pcre2_dep_opt.auto()) and not meson.is_cross_build()
   pcre2_dep = dependency('libpcre2-8', required: false, static: true)
   if not pcre2_dep.found()
     pcre2_dep = cc.find_library('pcre2', required: true, static: true)
   endif
 else
-  pcre2_dep = dependency('pcre2', 'pcre2_dep', version: '>=10.42', required: true, static: true)
+  pcre2_dep = dependency('pcre2', version: '>=10.42', required: true, static: true)
+endif
+
+if meson.is_cross_build()
+  pcre2_native_dep = dependency('pcre2_cross_native', required: true, static: true, native: true)
 endif
 
 # handle magic library
diff --git a/subprojects/packagefiles/pcre2_cross_native/meson.build b/subprojects/packagefiles/pcre2_cross_native/meson.build
new file mode 100644
index 00000000000..9e8dc206423
--- /dev/null
+++ b/subprojects/packagefiles/pcre2_cross_native/meson.build
@@ -0,0 +1,90 @@
+# Copy of PCRE2 library for the native version if a cross build happens.
+# Because Meson currently doesn't support subprojects to be native and non-native:
+# https://github.com/mesonbuild/meson/issues/10947
+
+project('pcre2_cross_native', 'c', version: '10.42')
+
+cc = meson.get_compiler('c')
+
+conf_data = configuration_data()
+
+pcre2_chartables = configure_file(input : 'src/pcre2_chartables.c.dist',
+  output : 'pcre2_chartables.c',
+  configuration : conf_data)
+
+pcre2_h = configure_file(input : 'src/pcre2.h.generic',
+  output : 'pcre2.h',
+  configuration : conf_data)
+
+config_h = configure_file(input : 'src/config.h.generic',
+  output : 'config.h',
+  configuration : conf_data)
+
+libpcre2_c_args = [
+  '-DHAVE_CONFIG_H', # Default values from config.h
+  '-DPCRE2_CODE_UNIT_WIDTH=8',
+  '-DHAVE_MEMMOVE',
+  '-DSUPPORT_PCRE2_8',
+  '-DSUPPORT_UNICODE',
+  '-fvisibility=default',
+]
+
+pcre2_files = [
+  'src/pcre2_auto_possess.c',
+  pcre2_chartables,
+  'src/pcre2_compile.c',
+  'src/pcre2_config.c',
+  'src/pcre2_context.c',
+  'src/pcre2_convert.c',
+  'src/pcre2_dfa_match.c',
+  'src/pcre2_error.c',
+  'src/pcre2_extuni.c',
+  'src/pcre2_find_bracket.c',
+  'src/pcre2_maketables.c',
+  'src/pcre2_match.c',
+  'src/pcre2_match_data.c',
+  'src/pcre2_newline.c',
+  'src/pcre2_ord2utf.c',
+  'src/pcre2_pattern_info.c',
+  'src/pcre2_script_run.c',
+  'src/pcre2_serialize.c',
+  'src/pcre2_string_utils.c',
+  'src/pcre2_study.c',
+  'src/pcre2_substitute.c',
+  'src/pcre2_substring.c',
+  'src/pcre2_tables.c',
+  'src/pcre2_ucd.c',
+  'src/pcre2_valid_utf.c',
+  'src/pcre2_xclass.c',
+]
+
+cpu_jit_supported = [ 'aarch64', 'arm', 'mips', 'mips64', 'ppc', 'ppc64', 'riscv32', 'riscv64', 's390x', 'x86', 'x86_64' ]
+
+# tcc doesn't support the MSVC asm syntax PCRE2 uses (`__asm { ... }`).
+# It is used in the JIT compiler code.
+if cc.get_id() != 'tcc' and target_machine.cpu_family() in cpu_jit_supported
+  libpcre2_c_args += ['-DSUPPORT_JIT']
+  pcre2_files += ['src/pcre2_jit_compile.c']
+endif
+
+if target_machine.system() == 'openbsd' or target_machine.system() == 'netbsd'
+  # jit compilation fails with "no more memory" if wx allocations are allowed.
+  libpcre2_c_args += ['-DSLJIT_WX_EXECUTABLE_ALLOCATOR']
+endif
+
+pcre2_includes = [
+  include_directories('.'),
+  include_directories('src/'),
+]
+
+libpcre2_cross_native = static_library('pcre2_cross_native', pcre2_files,
+  c_args: libpcre2_c_args,
+  include_directories: pcre2_includes,
+  install: false,
+  native: true,
+)
+
+pcre2_cross_native_dep = declare_dependency(
+  link_with: libpcre2_cross_native,
+  include_directories: pcre2_includes,
+)
diff --git a/subprojects/pcre2_cross_native.wrap b/subprojects/pcre2_cross_native.wrap
new file mode 100644
index 00000000000..d77f572ecaa
--- /dev/null
+++ b/subprojects/pcre2_cross_native.wrap
@@ -0,0 +1,9 @@
+[wrap-git]
+url = https://github.com/PCRE2Project/pcre2.git
+revision = 52c08847921a324c804cabf2814549f50bce1265
+directory = pcre2_cross_native
+patch_directory = pcre2_cross_native
+
+[provide]
+dependency_names = pcre2_cross_native
+pcre2_cross_native = pcre2_cross_native_dep