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MetaCerberus Databases

jhensl19 edited this page May 31, 2024 · 1 revision

All pre-formatted databases are present at OSF.

Database sources

Database Last Update Version Publication MetaCerberus Update Version
KEGG/KOfams 2024-01-01 Jan24 Aramaki et al. 2020 beta
FOAM/KOfams 2017 1 Prestat et al. 2014 beta
COG 2020 2020 Galperin et al. 2020 beta
dbCAN/CAZy 2023-08-02 12 Yin et al., 2012 beta
VOG 2017-03-03 80 Website beta
pVOG 2016 2016 Grazziotin et al. 2017 1.2
PHROG 2022-06-15 4 Terizan et al., 2021 1.2
PFAM 2023-09-12 36 Mistry et al. 2020 1.3
TIGRfams 2018-06-19 15 Haft et al. 2003 1.3
PGAPfams 2023-12-21 14 Tatusova et al. 2016 1.3
AMRFinder-fams 2024-02-05 2024-02-05 Feldgarden et al. 2021 1.3
NFixDB 2024-01-22 2 Bellanger et al. 2024 1.3
GVDB 2021 1 Aylward et al. 2021 1.3
Pads Arsenal 2019-09-09 1 Zhang et al. 2020 Coming soon
efam-XC 2021-05-21 1 Zayed et al. 2021 Coming soon
NMPFams 2021 1 Baltoumas et al. 2024 Coming soon
MEROPS 2017 1 Rawlings et al. 2018 Coming soon
FESNov 2024 1 Rodríguez del Río et al. 2024 Coming soon

Note

The KEGG database contains KOs related to Human disease. It is possible that these will show up in the results, even when analyzing microbes. eggNOG and FunGene database are coming soon. If you want a custom HMM build please let us know by email or leaving an issue.

Custom Database

To run a custom database, you need a HMM containing the protein family of interest and a metadata sheet describing the HMM required for look-up tables and downstream analysis. For the metadata information you need an ID that matches the HMM and a function or hierarchy. See example below.

Example Metadata sheet

ID Function
HMM1 Sugarase
HMM2 Coffease