diff --git a/.github/workflows/pypi.yml b/.github/workflows/pypi.yml
new file mode 100644
index 0000000..9159661
--- /dev/null
+++ b/.github/workflows/pypi.yml
@@ -0,0 +1,32 @@
+name: Publish Python Package to Pypi.org
+
+on:
+  release:
+    types: [published]
+
+permissions:
+  id-token: write
+
+jobs:
+  pypi-publish:
+    name: Release Python Package on Pypi.org
+    runs-on: ubuntu-latest
+    environment:
+      name: pypi
+      url: https://pypi.org/p/django-loci
+    permissions:
+      id-token: write
+    steps:
+    - uses: actions/checkout@v4
+    - name: Set up Python
+      uses: actions/setup-python@v5
+      with:
+        python-version: '3.10'
+    - name: Install dependencies
+      run: |
+        pip install -U pip
+        pip install build
+    - name: Build package
+      run: python -m build
+    - name: Publish package distributions to PyPI
+      uses: pypa/gh-action-pypi-publish@v1.9.0
diff --git a/setup.py b/setup.py
index 0fa93d7..3b21abc 100644
--- a/setup.py
+++ b/setup.py
@@ -1,7 +1,4 @@
 #!/usr/bin/env python
-import os
-import sys
-
 from setuptools import find_packages, setup
 
 from django_loci import get_version
@@ -26,19 +23,6 @@ def get_install_requires():
     return requirements
 
 
-if sys.argv[-1] == 'publish':
-    # delete any *.pyc, *.pyo and __pycache__
-    os.system('find . | grep -E "(__pycache__|\.pyc|\.pyo$)" | xargs rm -rf')
-    os.system("python setup.py sdist bdist_wheel")
-    os.system("twine upload -s dist/*")
-    os.system("rm -rf dist build")
-    args = {'version': get_version()}
-    print("You probably want to also tag the version now:")
-    print("  git tag -a %(version)s -m 'version %(version)s'" % args)
-    print("  git push --tags")
-    sys.exit()
-
-
 setup(
     name='django-loci',
     version=get_version(),