diff --git a/.github/workflows/docker-publish.yml b/.github/workflows/docker-publish.yml
deleted file mode 100644
index e50c863..0000000
--- a/.github/workflows/docker-publish.yml
+++ /dev/null
@@ -1,32 +0,0 @@
-name: Build and push docker image
-
-on:
-  push:
-    tags: [ 'v*.*.*' ]
-
-jobs:
-  push_to_registry:
-    environment: docker_build
-    runs-on: ubuntu-latest
-    steps:
-      -
-        name: Set env
-        run: echo "RELEASE_VERSION=${GITHUB_REF#refs/*/}" >> $GITHUB_ENV
-      -
-        name: Set up Docker Buildx
-        uses: docker/setup-buildx-action@v3
-      -
-        name: Login to GitHub Container Registry
-        uses: docker/login-action@v3
-        with:
-          registry: ghcr.io
-          username: ${{ github.repository_owner }}
-          password: ${{ secrets.GITHUB_TOKEN }}
-      -
-        name: Build and push
-        uses: docker/build-push-action@v6
-        with:
-          push: true
-          tags: |
-            ghcr.io/fhcrc/deenurp:latest
-            ghcr.io/fhcrc/deenurp:${{ env.RELEASE_VERSION }}
diff --git a/.github/workflows/test-publish.yml b/.github/workflows/test-publish.yml
new file mode 100644
index 0000000..b38698b
--- /dev/null
+++ b/.github/workflows/test-publish.yml
@@ -0,0 +1,90 @@
+---
+name: Run tests and deploy to registry
+
+on:
+  push:
+    branches:
+      - "*"
+    tags: 
+      - "v*.*.*"
+  pull_request:
+    branches:
+      - $default-branch
+
+env:
+  REGISTRY: ghcr.io
+  IMAGE_NAME: ${{ github.repository }}
+
+jobs:
+  unittests:
+    runs-on: ubuntu-latest
+    strategy:
+      matrix:
+        python-version: ["3.8", "3.9", "3.10", "3.11"]
+
+    steps:
+      - name: Checkout repository
+        uses: actions/checkout@v3
+
+      - uses: actions/checkout@v4
+      - run: |
+          python3 -m deenurp.test
+          tests/run.sh      
+    - name: Set up Python ${{ matrix.python-version }}
+        uses: actions/setup-python@v4
+        with:
+          python-version: ${{ matrix.python-version }}
+
+      - name: Install package and dependencies
+        run: |
+          python -m pip install --upgrade pip wheel
+          python -m pip install .
+
+      - name: Run tests
+        run: python -m unittest discover
+
+  deploy:
+      if: github.ref_type == 'tag'
+      needs: [unittests]
+      permissions:
+        contents: read
+        packages: write
+        id-token: write
+      runs-on: ubuntu-latest
+
+      steps:
+      - name: Checkout repo
+        uses: actions/checkout@v4
+
+      - name: Set up Docker Buildx
+        uses: docker/setup-buildx-action@v3
+
+      - name: Log into registry ${{ env.REGISTRY }}
+        uses: docker/login-action@v3
+        with:
+          registry: ${{ env.REGISTRY }}
+          username: ${{ github.actor }}
+          password: ${{ secrets.GITHUB_TOKEN }}
+
+      - name: Extract Docker metadata
+        id: meta
+        uses: docker/metadata-action@v5
+        with:
+          images: ${{ env.REGISTRY }}/${{ env.IMAGE_NAME }}
+
+      - name: Build and push
+        id: build-and-push
+        uses: docker/build-push-action@v6
+        with:
+          cache-from: type=gha
+          cache-to: type=gha,mode=max
+          context: .
+          labels: ${{ steps.meta.outputs.labels }}
+          push: true
+          tags: ${{ steps.meta.outputs.tags }}
+
+      - name: Sign the published Docker image
+        env:
+          DIGEST: ${{ steps.build-and-push.outputs.digest }}
+          TAGS: ${{ steps.meta.outputs.tags }}
+        run: echo "${TAGS}" | xargs -I {} cosign sign --yes {}@${DIGEST}
diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml
deleted file mode 100644
index 91ac9b0..0000000
--- a/.github/workflows/tests.yml
+++ /dev/null
@@ -1,40 +0,0 @@
-name: Run deenurp tests on deenurp image
-
-on: push
-
-jobs:
-  dev_image:
-    environment: docker_build
-    runs-on: ubuntu-latest
-    outputs:
-      sha_short: ${{ env.sha_short }}
-    steps:
-      -
-        name: Set env
-        run: echo "sha_short=`echo ${GITHUB_SHA} | cut -c1-7`" >> $GITHUB_ENV
-      -
-        name: Set up Docker Buildx
-        uses: docker/setup-buildx-action@v3
-      -
-        name: Login to GitHub Container Registry
-        uses: docker/login-action@v3
-        with:
-          registry: ghcr.io
-          username: ${{ github.repository_owner }}
-          password: ${{ secrets.GITHUB_TOKEN }}
-      -
-        name: Build and push
-        uses: docker/build-push-action@v6
-        with:
-          push: true
-          tags: ghcr.io/fhcrc/deenurp:${{ env.sha_short }}
-  test:
-    needs: [dev_image]
-    runs-on: ubuntu-latest
-    container:
-      image: ghcr.io/fhcrc/deenurp:${{ needs.dev_image.outputs.sha_short }}
-    steps:
-    - uses: actions/checkout@v4
-    - run: |
-        python3 -m deenurp.test
-        tests/run.sh