diff --git a/integration_test/myxql/constraints_test.exs b/integration_test/myxql/constraints_test.exs
new file mode 100644
index 00000000..2323823f
--- /dev/null
+++ b/integration_test/myxql/constraints_test.exs
@@ -0,0 +1,83 @@
+defmodule Ecto.Integration.ConstraintsTest do
+  use ExUnit.Case, async: true
+
+  import Ecto.Migrator, only: [up: 4]
+  alias Ecto.Integration.PoolRepo
+
+  defmodule ConstraintMigration do
+    use Ecto.Migration
+
+    @table table(:constraints_test)
+
+    def change do
+      create @table do
+        add :price, :integer
+        add :from, :integer
+        add :to, :integer
+      end
+
+      # Only valid after MySQL 8.0.19
+      create constraint(@table.name, :positive_price, check: "price > 0")
+    end
+  end
+
+  defmodule Constraint do
+    use Ecto.Integration.Schema
+
+    schema "constraints_test" do
+      field :price, :integer
+      field :from, :integer
+      field :to, :integer
+    end
+  end
+
+  @base_migration 2_000_000
+
+  setup_all do
+    ExUnit.CaptureLog.capture_log(fn ->
+      num = @base_migration + System.unique_integer([:positive])
+      up(PoolRepo, num, ConstraintMigration, log: false)
+    end)
+
+    :ok
+  end
+
+  @tag :create_constraint
+  test "check constraint" do
+    # When the changeset doesn't expect the db error
+    changeset = Ecto.Changeset.change(%Constraint{}, price: -10)
+    exception =
+      assert_raise Ecto.ConstraintError, ~r/constraint error when attempting to insert struct/, fn ->
+        PoolRepo.insert(changeset)
+      end
+
+    assert exception.message =~ "\"positive_price\" (check_constraint)"
+    assert exception.message =~ "The changeset has not defined any constraint."
+    assert exception.message =~ "call `check_constraint/3`"
+
+    # When the changeset does expect the db error, but doesn't give a custom message
+    {:error, changeset} =
+      changeset
+      |> Ecto.Changeset.check_constraint(:price, name: :positive_price)
+      |> PoolRepo.insert()
+    assert changeset.errors == [price: {"is invalid", [constraint: :check, constraint_name: "positive_price"]}]
+    assert changeset.data.__meta__.state == :built
+
+    # When the changeset does expect the db error and gives a custom message
+    changeset = Ecto.Changeset.change(%Constraint{}, price: -10)
+    {:error, changeset} =
+      changeset
+      |> Ecto.Changeset.check_constraint(:price, name: :positive_price, message: "price must be greater than 0")
+      |> PoolRepo.insert()
+    assert changeset.errors == [price: {"price must be greater than 0", [constraint: :check, constraint_name: "positive_price"]}]
+    assert changeset.data.__meta__.state == :built
+
+    # When the change does not violate the check constraint
+    changeset = Ecto.Changeset.change(%Constraint{}, price: 10, from: 100, to: 200)
+    {:ok, changeset} =
+      changeset
+      |> Ecto.Changeset.check_constraint(:price, name: :positive_price, message: "price must be greater than 0")
+      |> PoolRepo.insert()
+    assert is_integer(changeset.id)
+  end
+end
diff --git a/integration_test/myxql/test_helper.exs b/integration_test/myxql/test_helper.exs
index fb966982..4bede7b8 100644
--- a/integration_test/myxql/test_helper.exs
+++ b/integration_test/myxql/test_helper.exs
@@ -121,7 +121,7 @@ excludes = [
 if Version.match?(version, ">= 8.0.0") do
   ExUnit.configure(exclude: excludes)
 else
-  ExUnit.configure(exclude: [:values_list, :rename_column | excludes])
+  ExUnit.configure(exclude: [:create_constraint, :values_list, :rename_column | excludes])
 end
 
 :ok = Ecto.Migrator.up(TestRepo, 0, Ecto.Integration.Migration, log: false)
diff --git a/lib/ecto/adapters/myxql/connection.ex b/lib/ecto/adapters/myxql/connection.ex
index 31b334e5..4f1fb57c 100644
--- a/lib/ecto/adapters/myxql/connection.ex
+++ b/lib/ecto/adapters/myxql/connection.ex
@@ -78,6 +78,18 @@ if Code.ensure_loaded?(MyXQL) do
       end
     end
 
+    def to_constraints(
+          %MyXQL.Error{mysql: %{name: :ER_CHECK_CONSTRAINT_VIOLATED}, message: message},
+          _opts
+        ) do
+      with [_, quoted] <- :binary.split(message, ["Check constraint "]),
+           [_, constraint | _] <- :binary.split(quoted, @quotes, [:global]) do
+        [check: constraint]
+      else
+        _ -> []
+      end
+    end
+
     def to_constraints(_, _),
       do: []
 
@@ -1026,12 +1038,31 @@ if Code.ensure_loaded?(MyXQL) do
     def execute_ddl({:create_if_not_exists, %Index{}}),
       do: error!(nil, "MySQL adapter does not support create if not exists for index")
 
-    def execute_ddl({:create, %Constraint{check: check}}) when is_binary(check),
-      do: error!(nil, "MySQL adapter does not support check constraints")
+    def execute_ddl({:create, %Constraint{check: check} = constraint}) when is_binary(check) do
+      table_name = quote_name(constraint.prefix, constraint.table)
+      [["ALTER TABLE ", table_name, " ADD ", new_constraint_expr(constraint)]]
+    end
 
     def execute_ddl({:create, %Constraint{exclude: exclude}}) when is_binary(exclude),
       do: error!(nil, "MySQL adapter does not support exclusion constraints")
 
+    def execute_ddl({:drop, %Constraint{}, :cascade}),
+      do: error!(nil, "MySQL does not support `CASCADE` in `DROP CONSTRAINT` commands")
+
+    def execute_ddl({:drop, %Constraint{} = constraint, _}) do
+      [
+        [
+          "ALTER TABLE ",
+          quote_name(constraint.prefix, constraint.table),
+          " DROP CONSTRAINT ",
+          quote_name(constraint.name)
+        ]
+      ]
+    end
+
+    def execute_ddl({:drop_if_exists, %Constraint{}, _}),
+      do: error!(nil, "MySQL adapter does not support `drop_if_exists` for constraints")
+
     def execute_ddl({:drop, %Index{}, :cascade}),
       do: error!(nil, "MySQL adapter does not support cascade in drop index")
 
@@ -1047,12 +1078,6 @@ if Code.ensure_loaded?(MyXQL) do
       ]
     end
 
-    def execute_ddl({:drop, %Constraint{}, _}),
-      do: error!(nil, "MySQL adapter does not support constraints")
-
-    def execute_ddl({:drop_if_exists, %Constraint{}, _}),
-      do: error!(nil, "MySQL adapter does not support constraints")
-
     def execute_ddl({:drop_if_exists, %Index{}, _}),
       do: error!(nil, "MySQL adapter does not support drop if exists for index")
 
@@ -1244,6 +1269,17 @@ if Code.ensure_loaded?(MyXQL) do
     defp null_expr(true), do: " NULL"
     defp null_expr(_), do: []
 
+    defp new_constraint_expr(%Constraint{check: check} = constraint) when is_binary(check) do
+      [
+        "CONSTRAINT ",
+        quote_name(constraint.name),
+        " CHECK (",
+        check,
+        ")",
+        validate(constraint.validate)
+      ]
+    end
+
     defp default_expr({:ok, nil}),
       do: " DEFAULT NULL"
 
@@ -1401,6 +1437,9 @@ if Code.ensure_loaded?(MyXQL) do
     defp reference_on_update(:restrict), do: " ON UPDATE RESTRICT"
     defp reference_on_update(_), do: []
 
+    defp validate(false), do: " NOT ENFORCED"
+    defp validate(_), do: []
+
     ## Helpers
 
     defp get_source(query, sources, ix, source) do
@@ -1423,6 +1462,10 @@ if Code.ensure_loaded?(MyXQL) do
 
     defp maybe_add_column_names(_, name), do: name
 
+    defp quote_name(nil, name), do: quote_name(name)
+
+    defp quote_name(prefix, name), do: [quote_name(prefix), ?., quote_name(name)]
+
     defp quote_name(name) when is_atom(name) do
       quote_name(Atom.to_string(name))
     end
diff --git a/lib/ecto/migration.ex b/lib/ecto/migration.ex
index 52cdee91..5a7462c0 100644
--- a/lib/ecto/migration.ex
+++ b/lib/ecto/migration.ex
@@ -1491,11 +1491,34 @@ defmodule Ecto.Migration do
     * `:check` - A check constraint expression. Required when creating a check constraint.
     * `:exclude` - An exclusion constraint expression. Required when creating an exclusion constraint.
     * `:prefix` - The prefix for the table.
-    * `:validate` - Whether or not to validate the constraint on creation (true by default). Only
-       available in PostgreSQL, and should be followed by a command to validate the new constraint in
-       a following migration if false.
+    * `:validate` - Whether or not to validate the constraint on creation (true by default). See the section below for more information
     * `:comment` - adds a comment to the constraint.
 
+
+  ## Using `validate: false`
+
+  Validation/Enforcement of a constraint is enabled by default, but disabling on constraint
+  creation is supported by PostgreSQL, and MySQL, and can be done by setting `validate: false`.
+
+  Setting `validate: false` as an option can be useful, as the creation of a constraint will cause
+  a full table scan to check existing rows. The constraint will still be enforced for subsequent
+  inserts and updates, but should then be updated in a following command or migration to enforce
+  the new constraint.
+
+  Validating / Enforcing the constraint in a later command, or migration, can be done like so:
+
+  ```
+    def change do
+      # PostgreSQL
+      execute "ALTER TABLE products VALIDATE CONSTRAINT price_must_be_positive", ""
+
+      # MySQL
+      execute "ALTER TABLE products ALTER CONSTRAINT price_must_be_positive ENFORCED", ""
+    end
+  ```
+
+  See the [Safe Ecto Migrations guide](https://fly.io/phoenix-files/safe-ecto-migrations/) for an
+  in-depth explanation of the benefits of this approach.
   """
   def constraint(table, name, opts \\ [])
 
diff --git a/mix.exs b/mix.exs
index dd0c0cd3..a722130c 100644
--- a/mix.exs
+++ b/mix.exs
@@ -92,7 +92,7 @@ defmodule EctoSQL.MixProject do
     if path = System.get_env("MYXQL_PATH") do
       {:myxql, path: path}
     else
-      {:myxql, "~> 0.6", optional: true}
+      {:myxql, "~> 0.7", optional: true}
     end
   end
 
diff --git a/mix.lock b/mix.lock
index fb853ec5..2daca590 100644
--- a/mix.lock
+++ b/mix.lock
@@ -10,7 +10,7 @@
   "makeup": {:hex, :makeup, "1.1.2", "9ba8837913bdf757787e71c1581c21f9d2455f4dd04cfca785c70bbfff1a76a3", [:mix], [{:nimble_parsec, "~> 1.2.2 or ~> 1.3", [hex: :nimble_parsec, repo: "hexpm", optional: false]}], "hexpm", "cce1566b81fbcbd21eca8ffe808f33b221f9eee2cbc7a1706fc3da9ff18e6cac"},
   "makeup_elixir": {:hex, :makeup_elixir, "0.16.2", "627e84b8e8bf22e60a2579dad15067c755531fea049ae26ef1020cad58fe9578", [:mix], [{:makeup, "~> 1.0", [hex: :makeup, repo: "hexpm", optional: false]}, {:nimble_parsec, "~> 1.2.3 or ~> 1.3", [hex: :nimble_parsec, repo: "hexpm", optional: false]}], "hexpm", "41193978704763f6bbe6cc2758b84909e62984c7752b3784bd3c218bb341706b"},
   "makeup_erlang": {:hex, :makeup_erlang, "1.0.0", "6f0eff9c9c489f26b69b61440bf1b238d95badae49adac77973cbacae87e3c2e", [:mix], [{:makeup, "~> 1.0", [hex: :makeup, repo: "hexpm", optional: false]}], "hexpm", "ea7a9307de9d1548d2a72d299058d1fd2339e3d398560a0e46c27dab4891e4d2"},
-  "myxql": {:hex, :myxql, "0.6.3", "3d77683a09f1227abb8b73d66b275262235c5cae68182f0cfa5897d72a03700e", [:mix], [{:db_connection, "~> 2.4.1 or ~> 2.5", [hex: :db_connection, repo: "hexpm", optional: false]}, {:decimal, "~> 1.6 or ~> 2.0", [hex: :decimal, repo: "hexpm", optional: false]}, {:geo, "~> 3.4", [hex: :geo, repo: "hexpm", optional: true]}, {:jason, "~> 1.0", [hex: :jason, repo: "hexpm", optional: true]}, {:table, "~> 0.1.0", [hex: :table, repo: "hexpm", optional: true]}], "hexpm", "af9eb517ddaced5c5c28e8749015493757fd4413f2cfccea449c466d405d9f51"},
+  "myxql": {:hex, :myxql, "0.7.1", "7c7b75aa82227cd2bc9b7fbd4de774fb19a1cdb309c219f411f82ca8860f8e01", [:mix], [{:db_connection, "~> 2.4.1 or ~> 2.5", [hex: :db_connection, repo: "hexpm", optional: false]}, {:decimal, "~> 1.6 or ~> 2.0", [hex: :decimal, repo: "hexpm", optional: false]}, {:geo, "~> 3.4", [hex: :geo, repo: "hexpm", optional: true]}, {:jason, "~> 1.0", [hex: :jason, repo: "hexpm", optional: true]}, {:table, "~> 0.1.0", [hex: :table, repo: "hexpm", optional: true]}], "hexpm", "a491cdff53353a09b5850ac2d472816ebe19f76c30b0d36a43317a67c9004936"},
   "nimble_parsec": {:hex, :nimble_parsec, "1.4.0", "51f9b613ea62cfa97b25ccc2c1b4216e81df970acd8e16e8d1bdc58fef21370d", [:mix], [], "hexpm", "9c565862810fb383e9838c1dd2d7d2c437b3d13b267414ba6af33e50d2d1cf28"},
   "postgrex": {:hex, :postgrex, "0.17.3", "c92cda8de2033a7585dae8c61b1d420a1a1322421df84da9a82a6764580c503d", [:mix], [{:db_connection, "~> 2.1", [hex: :db_connection, repo: "hexpm", optional: false]}, {:decimal, "~> 1.5 or ~> 2.0", [hex: :decimal, repo: "hexpm", optional: false]}, {:jason, "~> 1.0", [hex: :jason, repo: "hexpm", optional: true]}, {:table, "~> 0.1.0", [hex: :table, repo: "hexpm", optional: true]}], "hexpm", "946cf46935a4fdca7a81448be76ba3503cff082df42c6ec1ff16a4bdfbfb098d"},
   "statistex": {:hex, :statistex, "1.0.0", "f3dc93f3c0c6c92e5f291704cf62b99b553253d7969e9a5fa713e5481cd858a5", [:mix], [], "hexpm", "ff9d8bee7035028ab4742ff52fc80a2aa35cece833cf5319009b52f1b5a86c27"},
diff --git a/test/ecto/adapters/myxql_test.exs b/test/ecto/adapters/myxql_test.exs
index 4baac56d..89da3fb4 100644
--- a/test/ecto/adapters/myxql_test.exs
+++ b/test/ecto/adapters/myxql_test.exs
@@ -1621,7 +1621,8 @@ defmodule Ecto.Adapters.MyXQLTest do
 
   # DDL
 
-  import Ecto.Migration, only: [table: 1, table: 2, index: 2, index: 3, constraint: 3]
+  import Ecto.Migration,
+    only: [table: 1, table: 2, index: 2, index: 3, constraint: 2, constraint: 3]
 
   test "executing a string during migration" do
     assert execute_ddl("example") == ["example"]
@@ -1963,23 +1964,6 @@ defmodule Ecto.Adapters.MyXQLTest do
     assert execute_ddl(drop) == [~s|DROP TABLE `foo`.`posts`|]
   end
 
-  test "drop constraint" do
-    assert_raise ArgumentError, ~r/MySQL adapter does not support constraints/, fn ->
-      execute_ddl(
-        {:drop, constraint(:products, "price_must_be_positive", prefix: "foo"), :restrict}
-      )
-    end
-  end
-
-  test "drop_if_exists constraint" do
-    assert_raise ArgumentError, ~r/MySQL adapter does not support constraints/, fn ->
-      execute_ddl(
-        {:drop_if_exists, constraint(:products, "price_must_be_positive", prefix: "foo"),
-         :restrict}
-      )
-    end
-  end
-
   test "alter table" do
     alter =
       {:alter, table(:posts),
@@ -2152,15 +2136,34 @@ defmodule Ecto.Adapters.MyXQLTest do
   end
 
   test "create constraints" do
-    assert_raise ArgumentError, "MySQL adapter does not support check constraints", fn ->
-      create = {:create, constraint(:products, "foo", check: "price")}
-      assert execute_ddl(create)
-    end
+    create = {:create, constraint(:products, "price_must_be_positive", check: "price > 0")}
 
-    assert_raise ArgumentError, "MySQL adapter does not support check constraints", fn ->
-      create = {:create, constraint(:products, "foo", check: "price", validate: false)}
-      assert execute_ddl(create)
-    end
+    assert execute_ddl(create) ==
+             [
+               ~s|ALTER TABLE `products` ADD CONSTRAINT `price_must_be_positive` CHECK (price > 0)|
+             ]
+
+    create =
+      {:create,
+       constraint(:products, "price_must_be_positive", check: "price > 0", prefix: "foo")}
+
+    assert execute_ddl(create) ==
+             [
+               ~s|ALTER TABLE `foo`.`products` ADD CONSTRAINT `price_must_be_positive` CHECK (price > 0)|
+             ]
+
+    create =
+      {:create,
+       constraint(:products, "price_must_be_positive",
+         check: "price > 0",
+         prefix: "foo",
+         validate: false
+       )}
+
+    assert execute_ddl(create) ==
+             [
+               ~s|ALTER TABLE `foo`.`products` ADD CONSTRAINT `price_must_be_positive` CHECK (price > 0) NOT ENFORCED|
+             ]
 
     assert_raise ArgumentError, "MySQL adapter does not support exclusion constraints", fn ->
       create = {:create, constraint(:products, "bar", exclude: "price")}
@@ -2173,6 +2176,37 @@ defmodule Ecto.Adapters.MyXQLTest do
     end
   end
 
+  test "drop constraint" do
+    drop = {:drop, constraint(:products, "price_must_be_positive"), :restrict}
+
+    assert execute_ddl(drop) ==
+             [~s|ALTER TABLE `products` DROP CONSTRAINT `price_must_be_positive`|]
+
+    drop = {:drop, constraint(:products, "price_must_be_positive", prefix: "foo"), :restrict}
+
+    assert execute_ddl(drop) ==
+             [~s|ALTER TABLE `foo`.`products` DROP CONSTRAINT `price_must_be_positive`|]
+
+    drop_cascade = {:drop, constraint(:products, "price_must_be_positive"), :cascade}
+
+    assert_raise ArgumentError,
+                 ~r/MySQL does not support `CASCADE` in `DROP CONSTRAINT` commands/,
+                 fn ->
+                   execute_ddl(drop_cascade)
+                 end
+  end
+
+  test "drop_if_exists constraint" do
+    assert_raise ArgumentError,
+                 ~r/MySQL adapter does not support `drop_if_exists` for constraints/,
+                 fn ->
+                   execute_ddl(
+                     {:drop_if_exists,
+                      constraint(:products, "price_must_be_positive", prefix: "foo"), :restrict}
+                   )
+                 end
+  end
+
   test "create an index using a different type" do
     create = {:create, index(:posts, [:permalink], using: :hash)}