diff --git a/rockcraft/services/lifecycle.py b/rockcraft/services/lifecycle.py
index 10639f877..880115ac6 100644
--- a/rockcraft/services/lifecycle.py
+++ b/rockcraft/services/lifecycle.py
@@ -119,4 +119,32 @@ def _post_prime_callback(step_info: StepInfo) -> bool:
     files = step_info.state.files if step_info.state else set()
 
     layers.prune_prime_files(prime_dir, files, base_layer_dir)
+
+    _python_usrmerge_fix(step_info)
+
     return True
+
+
+def _python_usrmerge_fix(step_info: StepInfo):
+    """Fix 'lib64' symlinks created by the Python plugin on ubuntu@24.04 projects."""
+    if step_info.project_info.base != "ubuntu@24.04":
+        # The issue only affects rocks with 24.04 bases.
+        return
+
+    state = step_info.state
+    if state is None:
+        # Can't inspect the files without a StepState.
+        return
+
+    if state.part_properties["plugin"] != "python":
+        # Be conservative and don't try to fix the files if they didn't come
+        # from the Python plugin.
+        return
+
+    if "lib64" not in state.files:
+        return
+
+    prime_dir = step_info.prime_dir
+    lib64 = prime_dir / "lib64"
+    if lib64.is_symlink() and lib64.readlink() == Path("lib"):
+        lib64.unlink()
diff --git a/tests/unit/services/test_lifecycle.py b/tests/unit/services/test_lifecycle.py
index 5480f791f..c9b78490b 100644
--- a/tests/unit/services/test_lifecycle.py
+++ b/tests/unit/services/test_lifecycle.py
@@ -13,11 +13,22 @@
 #
 # You should have received a copy of the GNU General Public License
 # along with this program.  If not, see <http://www.gnu.org/licenses/>.
+import os
 from pathlib import Path
 from unittest import mock
 
 import pytest
-from craft_parts import LifecycleManager, callbacks
+from craft_parts import (
+    LifecycleManager,
+    Part,
+    PartInfo,
+    ProjectDirs,
+    ProjectInfo,
+    Step,
+    StepInfo,
+    callbacks,
+)
+from craft_parts.state_manager.prime_state import PrimeState
 
 from rockcraft.services import lifecycle as lifecycle_module
 
@@ -78,3 +89,40 @@ def test_lifecycle_package_repositories(
     mock_callback.assert_called_once_with(
         lifecycle_module._install_overlay_repositories
     )
+
+
+def test_python_usrmerge_fix(tmp_path):
+    # The test setup is rather involved because we need to recreate/mock an
+    # exact set of circumstances here:
+
+    # 1) Create a project with 24.04 base;
+    dirs = ProjectDirs(work_dir=tmp_path)
+    project_info = ProjectInfo(
+        project_dirs=dirs,
+        application_name="test",
+        cache_dir=tmp_path,
+        strict_mode=False,
+        base="ubuntu@24.04",
+    )
+
+    # 2) Create a part using the Python plugin;
+    part = Part("p1", {"source": ".", "plugin": "python"})
+    part_info = PartInfo(project_info=project_info, part=part)
+
+    prime_dir = dirs.prime_dir
+    prime_dir.mkdir()
+
+    # 3) Setup a 'prime' directory where "lib64" is a symlink to "lib";
+    (prime_dir / "lib").mkdir()
+    (prime_dir / "lib64").symlink_to("lib")
+
+    # 4) Create a StepInfo that contains all of this.
+    step_info = StepInfo(part_info=part_info, step=Step.PRIME)
+    step_info.state = PrimeState(part_properties=part.spec.marshal(), files={"lib64"})
+
+    assert sorted(os.listdir(prime_dir)) == ["lib", "lib64"]
+
+    lifecycle_module._python_usrmerge_fix(step_info)
+
+    # After running the fix the "lib64" symlink must be gone
+    assert sorted(os.listdir(prime_dir)) == ["lib"]