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A concise description of why we're pursuing this task.
From Thomas:
I would seem like a very low hanging fruit for bystro would be to make running something like this - https://github.com/xihaoli/STAAR - for rare variant analysis easier. No need to parse a large file, etc. It seems like a reasonable approach to doing rare variant analysis – at least as good as any I’ve seen. I’d be keen to give it a whirl with ADSP’s data.
Completion Criteria:
What is the goal, and how do we know this task is accomplished?
Create a STAAR port in Python. Initial version does not need to be scalable past a single node
Implementation Summary
Give enough technical detail for a teammate to understand the proposed solution.
Background:
A concise description of why we're pursuing this task.
From Thomas:
I would seem like a very low hanging fruit for bystro would be to make running something like this - https://github.com/xihaoli/STAAR - for rare variant analysis easier. No need to parse a large file, etc. It seems like a reasonable approach to doing rare variant analysis – at least as good as any I’ve seen. I’d be keen to give it a whirl with ADSP’s data.
Completion Criteria:
What is the goal, and how do we know this task is accomplished?
Create a STAAR port in Python. Initial version does not need to be scalable past a single node
Implementation Summary
Give enough technical detail for a teammate to understand the proposed solution.
Implement the R package under https://github.com/bystrogenomics/bystro/tree/master/python/python/bystro/rare_variant
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