diff --git a/modules/cli/README.md b/modules/cli/README.md
index 582062a..d0ef1e8 100644
--- a/modules/cli/README.md
+++ b/modules/cli/README.md
@@ -201,6 +201,14 @@ The CLI uses four configuration files:
 Once `astria-go dev init` has been run, edit `~/.astria/tui-config.toml` to
 control the starting settings of the TUI app.
 
+The `highlight_color` and `border_color` accept both named colors and
+hexadecimal notation:
+
+```toml
+highlight_color = "blue"
+border_color = "#808080"
+```
+
 ### Set Service Environment Variables
 
 Edit `~/.astria/<instance>/config/base-config.toml` to add or change settings:
diff --git a/modules/cli/cmd/devrunner/config/constants.go b/modules/cli/cmd/devrunner/config/constants.go
index 66038af..a708e42 100644
--- a/modules/cli/cmd/devrunner/config/constants.go
+++ b/modules/cli/cmd/devrunner/config/constants.go
@@ -17,6 +17,8 @@ const (
 	DefaultTargetNetwork             = "local"
 	LocalNativeDenom                 = "nria"
 	DefaultTUIConfigName             = "tui-config.toml"
+	DefaultHighlightColor            = "blue"
+	DefaultBorderColor               = "gray"
 
 	// NOTE - do not include the 'v' at the beginning of the version number
 	CometbftVersion        = "0.38.8"
diff --git a/modules/cli/cmd/devrunner/config/tui.go b/modules/cli/cmd/devrunner/config/tui.go
index 4222787..7cf2e8c 100644
--- a/modules/cli/cmd/devrunner/config/tui.go
+++ b/modules/cli/cmd/devrunner/config/tui.go
@@ -12,7 +12,7 @@ import (
 // TUIConfig is the struct that holds the configuration and start state for the
 // TUI.
 type TUIConfig struct {
-	// Service settings
+	// Log viewer settings for services
 	AutoScroll bool `mapstructure:"auto_scroll" toml:"auto_scroll"`
 	WrapLines  bool `mapstructure:"wrap_lines" toml:"wrap_lines"`
 	Borderless bool `mapstructure:"borderless" toml:"borderless"`
@@ -27,6 +27,10 @@ type TUIConfig struct {
 	SequencerStartsMinimized bool `mapstructure:"sequencer_starts_minimized" toml:"sequencer_starts_minimized"`
 	// Generic services start minimized
 	GenericStartsMinimized bool `mapstructure:"generic_starts_minimized" toml:"generic_starts_minimized"`
+
+	// Accessibility settings
+	HighlightColor string `mapstructure:"highlight_color" toml:"highlight_color"`
+	BorderColor    string `mapstructure:"border_color" toml:"border_color"`
 }
 
 // DefaultTUIConfig returns a TUIConfig struct populated with all default
@@ -36,12 +40,14 @@ func DefaultTUIConfig() TUIConfig {
 		AutoScroll:               true,
 		WrapLines:                false,
 		Borderless:               false,
-		OverrideInstanceName:     "default",
+		OverrideInstanceName:     DefaultInstanceName,
 		CometBFTStartsMinimized:  false,
 		ConductorStartsMinimized: false,
 		ComposerStartsMinimized:  false,
 		SequencerStartsMinimized: false,
 		GenericStartsMinimized:   true,
+		HighlightColor:           DefaultHighlightColor,
+		BorderColor:              DefaultBorderColor,
 	}
 }
 
@@ -57,6 +63,8 @@ func (c TUIConfig) String() string {
 	output += fmt.Sprintf("ComposerStartsMinimized: %v, ", c.ComposerStartsMinimized)
 	output += fmt.Sprintf("SequencerStartsMinimized: %v, ", c.SequencerStartsMinimized)
 	output += fmt.Sprintf("GenericStartsMinimized: %v", c.GenericStartsMinimized)
+	output += fmt.Sprintf("HighlightColor: %s, ", c.HighlightColor)
+	output += fmt.Sprintf("BorderColor: %s", c.BorderColor)
 	output += "}"
 	return output
 }
diff --git a/modules/cli/cmd/devrunner/run.go b/modules/cli/cmd/devrunner/run.go
index 8d1fe40..b97ddd2 100644
--- a/modules/cli/cmd/devrunner/run.go
+++ b/modules/cli/cmd/devrunner/run.go
@@ -133,6 +133,8 @@ func runCmdHandler(c *cobra.Command, _ []string) {
 				LogPath:        filepath.Join(logsDir, appStartTime+"-astria-sequencer.log"),
 				ExportLogs:     exportLogs,
 				StartMinimized: tuiConfig.SequencerStartsMinimized,
+				HighlightColor: tuiConfig.HighlightColor,
+				BorderColor:    tuiConfig.BorderColor,
 			}
 			seqRunner = processrunner.NewProcessRunner(ctx, seqOpts)
 		case "composer":
@@ -147,6 +149,8 @@ func runCmdHandler(c *cobra.Command, _ []string) {
 				LogPath:        filepath.Join(logsDir, appStartTime+"-astria-composer.log"),
 				ExportLogs:     exportLogs,
 				StartMinimized: tuiConfig.ComposerStartsMinimized,
+				HighlightColor: tuiConfig.HighlightColor,
+				BorderColor:    tuiConfig.BorderColor,
 			}
 			compRunner = processrunner.NewProcessRunner(ctx, composerOpts)
 		case "conductor":
@@ -161,6 +165,8 @@ func runCmdHandler(c *cobra.Command, _ []string) {
 				LogPath:        filepath.Join(logsDir, appStartTime+"-astria-conductor.log"),
 				ExportLogs:     exportLogs,
 				StartMinimized: tuiConfig.ConductorStartsMinimized,
+				HighlightColor: tuiConfig.HighlightColor,
+				BorderColor:    tuiConfig.BorderColor,
 			}
 			condRunner = processrunner.NewProcessRunner(ctx, conductorOpts)
 		case "cometbft":
@@ -186,6 +192,8 @@ func runCmdHandler(c *cobra.Command, _ []string) {
 				LogPath:        filepath.Join(logsDir, appStartTime+"-cometbft.log"),
 				ExportLogs:     exportLogs,
 				StartMinimized: tuiConfig.CometBFTStartsMinimized,
+				HighlightColor: tuiConfig.HighlightColor,
+				BorderColor:    tuiConfig.BorderColor,
 			}
 			cometRunner = processrunner.NewProcessRunner(ctx, cometOpts)
 		default:
@@ -199,6 +207,8 @@ func runCmdHandler(c *cobra.Command, _ []string) {
 				LogPath:        filepath.Join(logsDir, appStartTime+"-"+service.Name+".log"),
 				ExportLogs:     exportLogs,
 				StartMinimized: tuiConfig.GenericStartsMinimized,
+				HighlightColor: tuiConfig.HighlightColor,
+				BorderColor:    tuiConfig.BorderColor,
 			}
 			genericRunner := processrunner.NewProcessRunner(ctx, genericOpts)
 			genericRunners = append(genericRunners, genericRunner)
diff --git a/modules/cli/internal/processrunner/processrunner.go b/modules/cli/internal/processrunner/processrunner.go
index 578f082..39db687 100644
--- a/modules/cli/internal/processrunner/processrunner.go
+++ b/modules/cli/internal/processrunner/processrunner.go
@@ -24,6 +24,8 @@ type ProcessRunner interface {
 	CanWriteToLog() bool
 	WriteToLog(data string) error
 	GetStartMinimized() bool
+	GetHighlightColor() string
+	GetBorderColor() string
 }
 
 // ProcessRunner is a struct that represents a process to be run.
@@ -56,6 +58,8 @@ type NewProcessRunnerOpts struct {
 	LogPath        string
 	ExportLogs     bool
 	StartMinimized bool
+	HighlightColor string
+	BorderColor    string
 }
 
 // NewProcessRunner creates a new ProcessRunner.
@@ -260,3 +264,11 @@ func (pr *processRunner) WriteToLog(data string) error {
 func (pr *processRunner) GetStartMinimized() bool {
 	return pr.opts.StartMinimized
 }
+
+func (pr *processRunner) GetHighlightColor() string {
+	return pr.opts.HighlightColor
+}
+
+func (pr *processRunner) GetBorderColor() string {
+	return pr.opts.BorderColor
+}
diff --git a/modules/cli/internal/testutils/mocks.go b/modules/cli/internal/testutils/mocks.go
index 56c1a43..dceb5a6 100644
--- a/modules/cli/internal/testutils/mocks.go
+++ b/modules/cli/internal/testutils/mocks.go
@@ -72,3 +72,11 @@ func (m *MockProcessRunner) WriteToLog(data string) error {
 func (m *MockProcessRunner) GetStartMinimized() bool {
 	return false
 }
+
+func (m *MockProcessRunner) GetHighlightColor() string {
+	return "blue"
+}
+
+func (m *MockProcessRunner) GetBorderColor() string {
+	return "gray"
+}
diff --git a/modules/cli/internal/ui/processpane.go b/modules/cli/internal/ui/processpane.go
index f0c4fd6..6941194 100644
--- a/modules/cli/internal/ui/processpane.go
+++ b/modules/cli/internal/ui/processpane.go
@@ -23,6 +23,9 @@ type ProcessPane struct {
 
 	Title       string
 	isMinimized bool
+
+	HighlightColor tcell.Color
+	BorderColor    tcell.Color
 }
 
 // NewProcessPane creates a new ProcessPane with a textView and processrunner.ProcessRunner
@@ -34,11 +37,22 @@ func NewProcessPane(tApp *tview.Application, pr processrunner.ProcessRunner) *Pr
 			tApp.Draw()
 		})
 	tv.SetBorder(true).
-		SetBorderColor(tcell.ColorGray).
 		SetTitle(pr.GetTitle())
 
 	ansiWriter := tview.ANSIWriter(tv)
 
+	highlightColor := tcell.GetColor(pr.GetHighlightColor())
+	if highlightColor == 0 {
+		log.Debugf("Highlight color %s could not be parsed, using default %s", pr.GetHighlightColor(), tcell.ColorBlue.Name())
+		highlightColor = tcell.ColorBlue
+	}
+
+	borderColor := tcell.GetColor(pr.GetBorderColor())
+	if borderColor == 0 {
+		log.Debugf("Border color %s could not be parsed, using default %s", pr.GetBorderColor(), tcell.ColorGray.Name())
+		borderColor = tcell.ColorGray
+	}
+
 	return &ProcessPane{
 		tApp:           tApp,
 		textView:       tv,
@@ -47,6 +61,8 @@ func NewProcessPane(tApp *tview.Application, pr processrunner.ProcessRunner) *Pr
 		Title:          pr.GetTitle(),
 		TickerInterval: 250,
 		isMinimized:    pr.GetStartMinimized(),
+		HighlightColor: highlightColor,
+		BorderColor:    borderColor,
 	}
 }
 
@@ -116,11 +132,12 @@ func (pp *ProcessPane) GetTextView() *tview.TextView {
 
 // Highlight highlights or unhighlights the ProcessPane's textView.
 func (pp *ProcessPane) Highlight(highlight bool) {
+	highlightTitleFormat := "[black:" + pp.HighlightColor.Name() + "]"
 	if highlight {
-		title := "[black:blue]" + pp.Title + "[::-]"
-		pp.textView.SetBorderColor(tcell.ColorBlue).SetTitle(title)
+		title := highlightTitleFormat + pp.Title + "[::-]"
+		pp.textView.SetBorderColor(pp.HighlightColor).SetTitle(title)
 	} else {
-		pp.textView.SetBorderColor(tcell.ColorGray).SetTitle(pp.Title)
+		pp.textView.SetBorderColor(pp.BorderColor).SetTitle(pp.Title)
 	}
 }