diff --git a/CHANGELOG.md b/CHANGELOG.md
index d994743fe..c69d38f62 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -7,6 +7,10 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ## [Unreleased]
 
+### Removed
+
+- BREAKING: remove `distributed` Skaffold profile [#768](https://github.com/Substra/substra-backend/pull/768)
+
 ## [0.42.2](https://github.com/Substra/substra-backend/releases/tag/0.42.2) 2023-10-18
 
 ### Changed
diff --git a/skaffold.yaml b/skaffold.yaml
index df84e211d..bb5ade701 100644
--- a/skaffold.yaml
+++ b/skaffold.yaml
@@ -83,23 +83,6 @@ profiles:
         path: /deploy/kubectl/manifests/3
       - op: remove
         path: /deploy/kubectl/manifests/1
-  - name: distributed
-    patches:
-      - op: add
-        path: /deploy/helm/releases/1/setValues/orchestrator.host
-        value: orchestrator-org-2-server.org-2.svc.cluster.local
-      - op: add
-        path: /deploy/helm/releases/0/setValues/server.livenessProbe.timeoutSeconds
-        value: 30
-      - op: add
-        path: /deploy/helm/releases/0/setValues/server.readinessProbe.timeoutSeconds
-        value: 30
-      - op: add
-        path: /deploy/helm/releases/1/setValues/server.livenessProbe.timeoutSeconds
-        value: 30
-      - op: add
-        path: /deploy/helm/releases/1/setValues/server.readinessProbe.timeoutSeconds
-        value: 30
   - name: persist-db
     patches:
       - op: add