diff --git a/src/Maui/Prism.Maui/Navigation/PageNavigationService.cs b/src/Maui/Prism.Maui/Navigation/PageNavigationService.cs
index da138875f..e4b3e5852 100644
--- a/src/Maui/Prism.Maui/Navigation/PageNavigationService.cs
+++ b/src/Maui/Prism.Maui/Navigation/PageNavigationService.cs
@@ -353,13 +353,27 @@ public virtual async Task<INavigationResult> NavigateFromAsync(string viewName,
             var navigationPages = currentPage.Navigation.NavigationStack.ToList();
             navigationPages.Reverse();
             var foundPage = navigationPages.FirstOrDefault(page => ViewModelLocator.GetNavigationName(page) == viewName);
-            var removePageCount = navigationPages.IndexOf(foundPage);
-
-            // Insert RemovePageSegment.
-            var routeString = route.ToString();
-            for (int i = 0; i < removePageCount; i++)
+            if (foundPage is null)
             {
-                AddToFront(navigationSegments, RemovePageSegment);
+                var page = currentPage;
+                while (page != null)
+                {
+                    if (page is not null && ViewModelLocator.GetNavigationName(page) == viewName)
+                        break;
+                    page = page.GetParentPage();
+                }
+                currentPage = page;
+            }
+            else
+            {
+                var removePageCount = navigationPages.IndexOf(foundPage);
+
+                // Insert RemovePageSegment.
+                var routeString = route.ToString();
+                for (int i = 0; i < removePageCount; i++)
+                {
+                    AddToFront(navigationSegments, RemovePageSegment);
+                }
             }
 
             await ProcessNavigation(currentPage, navigationSegments, parameters, null, null);
diff --git a/tests/Maui/Prism.DryIoc.Maui.Tests/Fixtures/Navigation/NavigationTests.cs b/tests/Maui/Prism.DryIoc.Maui.Tests/Fixtures/Navigation/NavigationTests.cs
index ba5ed8903..2d2a65156 100644
--- a/tests/Maui/Prism.DryIoc.Maui.Tests/Fixtures/Navigation/NavigationTests.cs
+++ b/tests/Maui/Prism.DryIoc.Maui.Tests/Fixtures/Navigation/NavigationTests.cs
@@ -510,7 +510,7 @@ public async Task Navigation_Animation_IsFalse()
     }
 
     [Fact]
-    public async Task Navigation_FromPageUsingRoute_OnNavigationPage()
+    public async Task Navigation_FromPageUsingRoute()
     {
         var mauiApp = CreateBuilder(prism => prism.CreateWindow("NavigationPage/MockViewA/MockViewB/MockViewC"))
             .Build();
@@ -526,6 +526,23 @@ public async Task Navigation_FromPageUsingRoute_OnNavigationPage()
         Assert.Equal("MockViewA/MockViewD/MockViewE", currentNavigationStackUri);
     }
 
+    [Fact]
+    public async Task Navigation_FromRootNavigationPageUsingRoute()
+    {
+        var mauiApp = CreateBuilder(prism => prism.CreateWindow("NavigationPage/MockViewA/MockViewB/MockViewC"))
+            .Build();
+        var window = GetWindow(mauiApp);
+        var navigationService = Prism.Navigation.Xaml.Navigation.GetNavigationService(window.CurrentPage);
+        var currentNavigationStackUri = string.Join("/", window.CurrentPage.Navigation.NavigationStack.Select(v => v.GetType().Name));
+        Assert.Equal("MockViewA/MockViewB/MockViewC", currentNavigationStackUri);
+
+        var result = await navigationService.NavigateFromAsync("NavigationPage", UriParsingHelper.Parse("MockViewD/MockViewE"), null);
+
+        Assert.True(result.Success);
+        currentNavigationStackUri = string.Join("/", window.CurrentPage.Navigation.NavigationStack.Select(v => v.GetType().Name));
+        Assert.Equal("MockViewD/MockViewE", currentNavigationStackUri);
+    }
+
     [Fact]
     public async Task Navigation_FromIntermediatePageUsingRoute()
     {