diff --git a/docs/tutorials/raw_readers.ipynb b/docs/tutorials/raw_readers.ipynb
new file mode 100644
index 0000000..f33d9a2
--- /dev/null
+++ b/docs/tutorials/raw_readers.ipynb
@@ -0,0 +1,1482 @@
+{
+ "cells": [
+  {
+   "cell_type": "markdown",
+   "metadata": {},
+   "source": [
+    "# Built-in Raw data readers"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "metadata": {},
+   "source": [
+    "AlphaRaw supports directly access Thermo's Raw data and Sciex's Wiff data by using PythonNet. PythonNet requires mono to be installed if the os is MacOS or Linux. See installation section of alpharaw (https://github.com/mannlabs/alpharaw). "
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "metadata": {},
+   "source": [
+    "## Thermo Raw\n",
+    "\n",
+    "`alpharaw.thermo.ThermoRawData` contains all functionalities to load the Themro's Raw data. To enable fast data loading, alpharaw enables multiprocessing when `process_count` > 1. This reader can load different kinds of spectrum information into columns of `spectrum_df`. By default, the columns are:\n",
+    "\n",
+    "- `spec_idx`: the index of a spectrum in the raw file, it starts from zero. Its value is the `scan number - 1`.\n",
+    "- `peak_start_idx`: the start row index of peaks in `peak_df` (see `mzml_reader.peak_df` below) for the spectrum.\n",
+    "- `peak_stop_idx`: the stop row index of peaks in `peak_df` (see `mzml_reader.peak_df` below) for the spectrum.\n",
+    "- `rt`: retention time in minutes. We will use `rt_sec` for retention time in seconds in alphaX ecosystem.\n",
+    "- `precursor_mz`: the precursor m/z of the given MS2 scans. For an MS1 scan, the value is always -1. For DIA MS2, the default value will be the isolation center of the MS2. And for DDA MS2, `precursor_mz` may refer to the mono-isotope m/z of the precursor when `precursor_charge` is not 0, otherwise isolation center.\n",
+    "- `precursor_charge`: For DIA, this value is always 0. For DDA, it can be nonzero when the mono-isotope m/z is determined.\n",
+    "- `isolation_lower_mz`: the lower (or left) m/z boundary of the isolation window.\n",
+    "- `isolation_upper_mz`: the upper (or right) m/z boundary of the isolation window.\n",
+    "- `ms_level`: MS1, MS2, ... it starts from one.\n",
+    "- `nce`: normalized collision energy designed by Thermo.\n",
+    "\n",
+    "There are also some optional spectrum columns (auxiliary_item) that can be loaded into the `spectrum_df`:\n",
+    "\n",
+    "- `injection_time`: `Ion Injection Time (ms)` in the scan header.\n",
+    "- `cv`: source fragmentation CV???\n",
+    "- `max_ion_time`: `Max. Ion Time (ms)` in the scan header.\n",
+    "- `agc_target`: `AGC target` in the scan header.\n",
+    "- `energy_ev`: `HCD Energy V` in the scan header. This is the real EV of the collision energy.\n",
+    "- `injection_optics_settling_time`: `Injection Optics Settling Time (ms)` in the scan header.\n",
+    "- `funnel_rf_level`: `Funnel RF Level` in the scan header.\n",
+    "- `faims_cv`: `FAIMS CV` in the scan header.\n",
+    "- `activation`: activation type, for example, HCD, CID, ETD, ...\n",
+    "- `analyzer`: analyzer type, for example FTMS, Astral, ITMS, ...\n",
+    "- `activation_id`: Thermo's built-in IDs of `activation` types.\n",
+    "- `analyzer_id`: Thermo's built-in IDs of `analyzer` types."
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 1,
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/html": [
+       "<div>\n",
+       "<style scoped>\n",
+       "    .dataframe tbody tr th:only-of-type {\n",
+       "        vertical-align: middle;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe tbody tr th {\n",
+       "        vertical-align: top;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe thead th {\n",
+       "        text-align: right;\n",
+       "    }\n",
+       "</style>\n",
+       "<table border=\"1\" class=\"dataframe\">\n",
+       "  <thead>\n",
+       "    <tr style=\"text-align: right;\">\n",
+       "      <th></th>\n",
+       "      <th>spec_idx</th>\n",
+       "      <th>peak_start_idx</th>\n",
+       "      <th>peak_stop_idx</th>\n",
+       "      <th>rt</th>\n",
+       "      <th>precursor_mz</th>\n",
+       "      <th>precursor_charge</th>\n",
+       "      <th>isolation_lower_mz</th>\n",
+       "      <th>isolation_upper_mz</th>\n",
+       "      <th>ms_level</th>\n",
+       "      <th>nce</th>\n",
+       "      <th>...</th>\n",
+       "      <th>max_ion_time</th>\n",
+       "      <th>agc_target</th>\n",
+       "      <th>energy_ev</th>\n",
+       "      <th>injection_optics_settling_time</th>\n",
+       "      <th>funnel_rf_level</th>\n",
+       "      <th>faims_cv</th>\n",
+       "      <th>activation</th>\n",
+       "      <th>analyzer</th>\n",
+       "      <th>activation_id</th>\n",
+       "      <th>analyzer_id</th>\n",
+       "    </tr>\n",
+       "  </thead>\n",
+       "  <tbody>\n",
+       "    <tr>\n",
+       "      <th>0</th>\n",
+       "      <td>0</td>\n",
+       "      <td>0</td>\n",
+       "      <td>254</td>\n",
+       "      <td>0.002983</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>25.0</td>\n",
+       "      <td>3000000</td>\n",
+       "      <td>0.000000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>MS1</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>255</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>1</th>\n",
+       "      <td>1</td>\n",
+       "      <td>254</td>\n",
+       "      <td>665</td>\n",
+       "      <td>0.006392</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>25.0</td>\n",
+       "      <td>3000000</td>\n",
+       "      <td>0.000000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>MS1</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>255</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>2</th>\n",
+       "      <td>2</td>\n",
+       "      <td>665</td>\n",
+       "      <td>1131</td>\n",
+       "      <td>0.009808</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>25.0</td>\n",
+       "      <td>3000000</td>\n",
+       "      <td>0.000000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>MS1</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>255</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3</th>\n",
+       "      <td>3</td>\n",
+       "      <td>1131</td>\n",
+       "      <td>1663</td>\n",
+       "      <td>0.013224</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>25.0</td>\n",
+       "      <td>3000000</td>\n",
+       "      <td>0.000000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>MS1</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>255</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>4</th>\n",
+       "      <td>4</td>\n",
+       "      <td>1663</td>\n",
+       "      <td>2169</td>\n",
+       "      <td>0.016641</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>25.0</td>\n",
+       "      <td>3000000</td>\n",
+       "      <td>0.000000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>MS1</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>255</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>...</th>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3932</th>\n",
+       "      <td>3932</td>\n",
+       "      <td>1100271</td>\n",
+       "      <td>1101512</td>\n",
+       "      <td>5.994985</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>25.0</td>\n",
+       "      <td>3000000</td>\n",
+       "      <td>0.000000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>MS1</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>255</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3933</th>\n",
+       "      <td>3933</td>\n",
+       "      <td>1101512</td>\n",
+       "      <td>1101528</td>\n",
+       "      <td>5.997334</td>\n",
+       "      <td>362.537140</td>\n",
+       "      <td>0</td>\n",
+       "      <td>361.837140</td>\n",
+       "      <td>363.237140</td>\n",
+       "      <td>2</td>\n",
+       "      <td>30.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>28.0</td>\n",
+       "      <td>100000</td>\n",
+       "      <td>16.500000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>HCD</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>5</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3934</th>\n",
+       "      <td>3934</td>\n",
+       "      <td>1101528</td>\n",
+       "      <td>1102758</td>\n",
+       "      <td>5.998843</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>25.0</td>\n",
+       "      <td>3000000</td>\n",
+       "      <td>0.000000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>MS1</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>255</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3935</th>\n",
+       "      <td>3935</td>\n",
+       "      <td>1102758</td>\n",
+       "      <td>1102771</td>\n",
+       "      <td>6.001193</td>\n",
+       "      <td>425.326569</td>\n",
+       "      <td>0</td>\n",
+       "      <td>424.626569</td>\n",
+       "      <td>426.026569</td>\n",
+       "      <td>2</td>\n",
+       "      <td>30.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>28.0</td>\n",
+       "      <td>100000</td>\n",
+       "      <td>18.690001</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>HCD</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>5</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3936</th>\n",
+       "      <td>3936</td>\n",
+       "      <td>1102771</td>\n",
+       "      <td>1103989</td>\n",
+       "      <td>6.002935</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>-1.000000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>...</td>\n",
+       "      <td>25.0</td>\n",
+       "      <td>3000000</td>\n",
+       "      <td>0.000000</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>40.0</td>\n",
+       "      <td>0.0</td>\n",
+       "      <td>MS1</td>\n",
+       "      <td>FTMS</td>\n",
+       "      <td>255</td>\n",
+       "      <td>4</td>\n",
+       "    </tr>\n",
+       "  </tbody>\n",
+       "</table>\n",
+       "<p>3937 rows × 22 columns</p>\n",
+       "</div>"
+      ],
+      "text/plain": [
+       "      spec_idx  peak_start_idx  peak_stop_idx        rt  precursor_mz  \\\n",
+       "0            0               0            254  0.002983     -1.000000   \n",
+       "1            1             254            665  0.006392     -1.000000   \n",
+       "2            2             665           1131  0.009808     -1.000000   \n",
+       "3            3            1131           1663  0.013224     -1.000000   \n",
+       "4            4            1663           2169  0.016641     -1.000000   \n",
+       "...        ...             ...            ...       ...           ...   \n",
+       "3932      3932         1100271        1101512  5.994985     -1.000000   \n",
+       "3933      3933         1101512        1101528  5.997334    362.537140   \n",
+       "3934      3934         1101528        1102758  5.998843     -1.000000   \n",
+       "3935      3935         1102758        1102771  6.001193    425.326569   \n",
+       "3936      3936         1102771        1103989  6.002935     -1.000000   \n",
+       "\n",
+       "      precursor_charge  isolation_lower_mz  isolation_upper_mz  ms_level  \\\n",
+       "0                    0           -1.000000           -1.000000         1   \n",
+       "1                    0           -1.000000           -1.000000         1   \n",
+       "2                    0           -1.000000           -1.000000         1   \n",
+       "3                    0           -1.000000           -1.000000         1   \n",
+       "4                    0           -1.000000           -1.000000         1   \n",
+       "...                ...                 ...                 ...       ...   \n",
+       "3932                 0           -1.000000           -1.000000         1   \n",
+       "3933                 0          361.837140          363.237140         2   \n",
+       "3934                 0           -1.000000           -1.000000         1   \n",
+       "3935                 0          424.626569          426.026569         2   \n",
+       "3936                 0           -1.000000           -1.000000         1   \n",
+       "\n",
+       "       nce  ...  max_ion_time  agc_target  energy_ev  \\\n",
+       "0      0.0  ...          25.0     3000000   0.000000   \n",
+       "1      0.0  ...          25.0     3000000   0.000000   \n",
+       "2      0.0  ...          25.0     3000000   0.000000   \n",
+       "3      0.0  ...          25.0     3000000   0.000000   \n",
+       "4      0.0  ...          25.0     3000000   0.000000   \n",
+       "...    ...  ...           ...         ...        ...   \n",
+       "3932   0.0  ...          25.0     3000000   0.000000   \n",
+       "3933  30.0  ...          28.0      100000  16.500000   \n",
+       "3934   0.0  ...          25.0     3000000   0.000000   \n",
+       "3935  30.0  ...          28.0      100000  18.690001   \n",
+       "3936   0.0  ...          25.0     3000000   0.000000   \n",
+       "\n",
+       "      injection_optics_settling_time  funnel_rf_level  faims_cv  activation  \\\n",
+       "0                                0.0             40.0       0.0         MS1   \n",
+       "1                                0.0             40.0       0.0         MS1   \n",
+       "2                                0.0             40.0       0.0         MS1   \n",
+       "3                                0.0             40.0       0.0         MS1   \n",
+       "4                                0.0             40.0       0.0         MS1   \n",
+       "...                              ...              ...       ...         ...   \n",
+       "3932                             0.0             40.0       0.0         MS1   \n",
+       "3933                             0.0             40.0       0.0         HCD   \n",
+       "3934                             0.0             40.0       0.0         MS1   \n",
+       "3935                             0.0             40.0       0.0         HCD   \n",
+       "3936                             0.0             40.0       0.0         MS1   \n",
+       "\n",
+       "      analyzer activation_id analyzer_id  \n",
+       "0         FTMS           255           4  \n",
+       "1         FTMS           255           4  \n",
+       "2         FTMS           255           4  \n",
+       "3         FTMS           255           4  \n",
+       "4         FTMS           255           4  \n",
+       "...        ...           ...         ...  \n",
+       "3932      FTMS           255           4  \n",
+       "3933      FTMS             5           4  \n",
+       "3934      FTMS           255           4  \n",
+       "3935      FTMS             5           4  \n",
+       "3936      FTMS           255           4  \n",
+       "\n",
+       "[3937 rows x 22 columns]"
+      ]
+     },
+     "execution_count": 1,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "from alpharaw.thermo import ThermoRawData\n",
+    "\n",
+    "raw_data = ThermoRawData(\n",
+    "    process_count=1,\n",
+    "    auxiliary_items=[\n",
+    "        \"injection_time\", \"cv\",\n",
+    "        \"max_ion_time\", \"agc_target\", \"energy_ev\",\n",
+    "        \"injection_optics_settling_time\", \n",
+    "        \"funnel_rf_level\", \"faims_cv\",\n",
+    "        \"activation\", \"analyzer\",\n",
+    "        \"activation_id\", \"analyzer_id\",\n",
+    "        # \"multinotch\",\n",
+    "    ]\n",
+    ")\n",
+    "raw_data.import_raw(\"../../nbs_tests/test_data/iRT.raw\")\n",
+    "raw_data.spectrum_df"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "metadata": {},
+   "source": [
+    "## Sciex Wiff\n",
+    "\n",
+    "AlphaRaw can access basic scan (spectrum) information of Sciex Wiff data. And the peaks are usually not centroided."
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 2,
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/html": [
+       "<div>\n",
+       "<style scoped>\n",
+       "    .dataframe tbody tr th:only-of-type {\n",
+       "        vertical-align: middle;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe tbody tr th {\n",
+       "        vertical-align: top;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe thead th {\n",
+       "        text-align: right;\n",
+       "    }\n",
+       "</style>\n",
+       "<table border=\"1\" class=\"dataframe\">\n",
+       "  <thead>\n",
+       "    <tr style=\"text-align: right;\">\n",
+       "      <th></th>\n",
+       "      <th>spec_idx</th>\n",
+       "      <th>peak_start_idx</th>\n",
+       "      <th>peak_stop_idx</th>\n",
+       "      <th>rt</th>\n",
+       "      <th>ms_level</th>\n",
+       "      <th>precursor_mz</th>\n",
+       "      <th>precursor_charge</th>\n",
+       "      <th>isolation_lower_mz</th>\n",
+       "      <th>isolation_upper_mz</th>\n",
+       "      <th>nce</th>\n",
+       "    </tr>\n",
+       "  </thead>\n",
+       "  <tbody>\n",
+       "    <tr>\n",
+       "      <th>0</th>\n",
+       "      <td>0</td>\n",
+       "      <td>0</td>\n",
+       "      <td>100</td>\n",
+       "      <td>0.000417</td>\n",
+       "      <td>1</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.0</td>\n",
+       "      <td>-1.0</td>\n",
+       "      <td>0.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>1</th>\n",
+       "      <td>1</td>\n",
+       "      <td>100</td>\n",
+       "      <td>447</td>\n",
+       "      <td>0.001133</td>\n",
+       "      <td>2</td>\n",
+       "      <td>403.55</td>\n",
+       "      <td>0</td>\n",
+       "      <td>399.5</td>\n",
+       "      <td>407.6</td>\n",
+       "      <td>19.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>2</th>\n",
+       "      <td>2</td>\n",
+       "      <td>447</td>\n",
+       "      <td>924</td>\n",
+       "      <td>0.001383</td>\n",
+       "      <td>2</td>\n",
+       "      <td>411.25</td>\n",
+       "      <td>0</td>\n",
+       "      <td>406.6</td>\n",
+       "      <td>415.9</td>\n",
+       "      <td>20.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3</th>\n",
+       "      <td>3</td>\n",
+       "      <td>924</td>\n",
+       "      <td>1286</td>\n",
+       "      <td>0.001650</td>\n",
+       "      <td>2</td>\n",
+       "      <td>419.25</td>\n",
+       "      <td>0</td>\n",
+       "      <td>414.9</td>\n",
+       "      <td>423.6</td>\n",
+       "      <td>20.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>4</th>\n",
+       "      <td>4</td>\n",
+       "      <td>1286</td>\n",
+       "      <td>1943</td>\n",
+       "      <td>0.001900</td>\n",
+       "      <td>2</td>\n",
+       "      <td>426.95</td>\n",
+       "      <td>0</td>\n",
+       "      <td>422.6</td>\n",
+       "      <td>431.3</td>\n",
+       "      <td>20.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>...</th>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "      <td>...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>42232</th>\n",
+       "      <td>42232</td>\n",
+       "      <td>73839218</td>\n",
+       "      <td>73841218</td>\n",
+       "      <td>11.627550</td>\n",
+       "      <td>2</td>\n",
+       "      <td>715.15</td>\n",
+       "      <td>0</td>\n",
+       "      <td>711.1</td>\n",
+       "      <td>719.2</td>\n",
+       "      <td>34.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>42233</th>\n",
+       "      <td>42233</td>\n",
+       "      <td>73841218</td>\n",
+       "      <td>73843218</td>\n",
+       "      <td>11.627817</td>\n",
+       "      <td>2</td>\n",
+       "      <td>722.30</td>\n",
+       "      <td>0</td>\n",
+       "      <td>718.2</td>\n",
+       "      <td>726.4</td>\n",
+       "      <td>35.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>42234</th>\n",
+       "      <td>42234</td>\n",
+       "      <td>73843218</td>\n",
+       "      <td>73845218</td>\n",
+       "      <td>11.628067</td>\n",
+       "      <td>2</td>\n",
+       "      <td>729.70</td>\n",
+       "      <td>0</td>\n",
+       "      <td>725.4</td>\n",
+       "      <td>734.0</td>\n",
+       "      <td>35.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>42235</th>\n",
+       "      <td>42235</td>\n",
+       "      <td>73845218</td>\n",
+       "      <td>73847218</td>\n",
+       "      <td>11.628317</td>\n",
+       "      <td>2</td>\n",
+       "      <td>737.35</td>\n",
+       "      <td>0</td>\n",
+       "      <td>733.0</td>\n",
+       "      <td>741.7</td>\n",
+       "      <td>35.0</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>42236</th>\n",
+       "      <td>42236</td>\n",
+       "      <td>73847218</td>\n",
+       "      <td>73849218</td>\n",
+       "      <td>11.628583</td>\n",
+       "      <td>2</td>\n",
+       "      <td>745.05</td>\n",
+       "      <td>0</td>\n",
+       "      <td>740.7</td>\n",
+       "      <td>749.4</td>\n",
+       "      <td>36.0</td>\n",
+       "    </tr>\n",
+       "  </tbody>\n",
+       "</table>\n",
+       "<p>42237 rows × 10 columns</p>\n",
+       "</div>"
+      ],
+      "text/plain": [
+       "       spec_idx  peak_start_idx  peak_stop_idx         rt  ms_level  \\\n",
+       "0             0               0            100   0.000417         1   \n",
+       "1             1             100            447   0.001133         2   \n",
+       "2             2             447            924   0.001383         2   \n",
+       "3             3             924           1286   0.001650         2   \n",
+       "4             4            1286           1943   0.001900         2   \n",
+       "...         ...             ...            ...        ...       ...   \n",
+       "42232     42232        73839218       73841218  11.627550         2   \n",
+       "42233     42233        73841218       73843218  11.627817         2   \n",
+       "42234     42234        73843218       73845218  11.628067         2   \n",
+       "42235     42235        73845218       73847218  11.628317         2   \n",
+       "42236     42236        73847218       73849218  11.628583         2   \n",
+       "\n",
+       "       precursor_mz  precursor_charge  isolation_lower_mz  isolation_upper_mz  \\\n",
+       "0             -1.00                 0                -1.0                -1.0   \n",
+       "1            403.55                 0               399.5               407.6   \n",
+       "2            411.25                 0               406.6               415.9   \n",
+       "3            419.25                 0               414.9               423.6   \n",
+       "4            426.95                 0               422.6               431.3   \n",
+       "...             ...               ...                 ...                 ...   \n",
+       "42232        715.15                 0               711.1               719.2   \n",
+       "42233        722.30                 0               718.2               726.4   \n",
+       "42234        729.70                 0               725.4               734.0   \n",
+       "42235        737.35                 0               733.0               741.7   \n",
+       "42236        745.05                 0               740.7               749.4   \n",
+       "\n",
+       "        nce  \n",
+       "0       0.0  \n",
+       "1      19.0  \n",
+       "2      20.0  \n",
+       "3      20.0  \n",
+       "4      20.0  \n",
+       "...     ...  \n",
+       "42232  34.0  \n",
+       "42233  35.0  \n",
+       "42234  35.0  \n",
+       "42235  35.0  \n",
+       "42236  36.0  \n",
+       "\n",
+       "[42237 rows x 10 columns]"
+      ]
+     },
+     "execution_count": 2,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "from alpharaw.sciex import SciexWiffData\n",
+    "\n",
+    "wiff_data = SciexWiffData()\n",
+    "wiff_data.import_raw(\n",
+    "    \"../../nbs_tests/test_data/02112022_Zeno1_TiHe_DIAMA_HeLa_200ng_EVO5_01.wiff\"\n",
+    ")\n",
+    "wiff_data.spectrum_df"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "metadata": {},
+   "source": [
+    "## mzML\n",
+    "\n",
+    "mzML is partially supported, the basic spectrum information is extracted."
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 3,
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/html": [
+       "<div>\n",
+       "<style scoped>\n",
+       "    .dataframe tbody tr th:only-of-type {\n",
+       "        vertical-align: middle;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe tbody tr th {\n",
+       "        vertical-align: top;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe thead th {\n",
+       "        text-align: right;\n",
+       "    }\n",
+       "</style>\n",
+       "<table border=\"1\" class=\"dataframe\">\n",
+       "  <thead>\n",
+       "    <tr style=\"text-align: right;\">\n",
+       "      <th></th>\n",
+       "      <th>spec_idx</th>\n",
+       "      <th>peak_start_idx</th>\n",
+       "      <th>peak_stop_idx</th>\n",
+       "      <th>rt</th>\n",
+       "      <th>precursor_mz</th>\n",
+       "      <th>precursor_charge</th>\n",
+       "      <th>isolation_lower_mz</th>\n",
+       "      <th>isolation_upper_mz</th>\n",
+       "      <th>ms_level</th>\n",
+       "    </tr>\n",
+       "  </thead>\n",
+       "  <tbody>\n",
+       "    <tr>\n",
+       "      <th>0</th>\n",
+       "      <td>0</td>\n",
+       "      <td>0</td>\n",
+       "      <td>10739</td>\n",
+       "      <td>0.004935</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>1</th>\n",
+       "      <td>1</td>\n",
+       "      <td>10739</td>\n",
+       "      <td>25554</td>\n",
+       "      <td>0.007897</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>2</th>\n",
+       "      <td>2</td>\n",
+       "      <td>25554</td>\n",
+       "      <td>26039</td>\n",
+       "      <td>0.011218</td>\n",
+       "      <td>810.79</td>\n",
+       "      <td>0</td>\n",
+       "      <td>810.29</td>\n",
+       "      <td>811.29</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3</th>\n",
+       "      <td>3</td>\n",
+       "      <td>26039</td>\n",
+       "      <td>27045</td>\n",
+       "      <td>0.022838</td>\n",
+       "      <td>837.34</td>\n",
+       "      <td>0</td>\n",
+       "      <td>836.84</td>\n",
+       "      <td>837.84</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>4</th>\n",
+       "      <td>4</td>\n",
+       "      <td>27045</td>\n",
+       "      <td>27882</td>\n",
+       "      <td>0.034925</td>\n",
+       "      <td>725.36</td>\n",
+       "      <td>0</td>\n",
+       "      <td>724.86</td>\n",
+       "      <td>725.86</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>5</th>\n",
+       "      <td>5</td>\n",
+       "      <td>27882</td>\n",
+       "      <td>28532</td>\n",
+       "      <td>0.048620</td>\n",
+       "      <td>558.87</td>\n",
+       "      <td>0</td>\n",
+       "      <td>558.37</td>\n",
+       "      <td>559.37</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>6</th>\n",
+       "      <td>6</td>\n",
+       "      <td>28532</td>\n",
+       "      <td>29294</td>\n",
+       "      <td>0.061923</td>\n",
+       "      <td>812.33</td>\n",
+       "      <td>0</td>\n",
+       "      <td>811.83</td>\n",
+       "      <td>812.83</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>7</th>\n",
+       "      <td>7</td>\n",
+       "      <td>29294</td>\n",
+       "      <td>37374</td>\n",
+       "      <td>0.075015</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>8</th>\n",
+       "      <td>8</td>\n",
+       "      <td>37374</td>\n",
+       "      <td>54285</td>\n",
+       "      <td>0.077788</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>9</th>\n",
+       "      <td>9</td>\n",
+       "      <td>54285</td>\n",
+       "      <td>54837</td>\n",
+       "      <td>0.081203</td>\n",
+       "      <td>810.75</td>\n",
+       "      <td>0</td>\n",
+       "      <td>810.25</td>\n",
+       "      <td>811.25</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>10</th>\n",
+       "      <td>10</td>\n",
+       "      <td>54837</td>\n",
+       "      <td>55778</td>\n",
+       "      <td>0.092903</td>\n",
+       "      <td>837.96</td>\n",
+       "      <td>0</td>\n",
+       "      <td>837.46</td>\n",
+       "      <td>838.46</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>11</th>\n",
+       "      <td>11</td>\n",
+       "      <td>55778</td>\n",
+       "      <td>56413</td>\n",
+       "      <td>0.104803</td>\n",
+       "      <td>644.06</td>\n",
+       "      <td>0</td>\n",
+       "      <td>643.56</td>\n",
+       "      <td>644.56</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>12</th>\n",
+       "      <td>12</td>\n",
+       "      <td>56413</td>\n",
+       "      <td>57205</td>\n",
+       "      <td>0.117215</td>\n",
+       "      <td>725.23</td>\n",
+       "      <td>0</td>\n",
+       "      <td>724.73</td>\n",
+       "      <td>725.73</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>13</th>\n",
+       "      <td>13</td>\n",
+       "      <td>57205</td>\n",
+       "      <td>57874</td>\n",
+       "      <td>0.130022</td>\n",
+       "      <td>559.19</td>\n",
+       "      <td>0</td>\n",
+       "      <td>558.69</td>\n",
+       "      <td>559.69</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>14</th>\n",
+       "      <td>14</td>\n",
+       "      <td>57874</td>\n",
+       "      <td>66994</td>\n",
+       "      <td>0.143452</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>15</th>\n",
+       "      <td>15</td>\n",
+       "      <td>66994</td>\n",
+       "      <td>81922</td>\n",
+       "      <td>0.146408</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>16</th>\n",
+       "      <td>16</td>\n",
+       "      <td>81922</td>\n",
+       "      <td>82501</td>\n",
+       "      <td>0.149755</td>\n",
+       "      <td>811.41</td>\n",
+       "      <td>0</td>\n",
+       "      <td>810.91</td>\n",
+       "      <td>811.91</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>17</th>\n",
+       "      <td>17</td>\n",
+       "      <td>82501</td>\n",
+       "      <td>83417</td>\n",
+       "      <td>0.161442</td>\n",
+       "      <td>837.36</td>\n",
+       "      <td>0</td>\n",
+       "      <td>836.86</td>\n",
+       "      <td>837.86</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>18</th>\n",
+       "      <td>18</td>\n",
+       "      <td>83417</td>\n",
+       "      <td>84087</td>\n",
+       "      <td>0.173370</td>\n",
+       "      <td>643.80</td>\n",
+       "      <td>0</td>\n",
+       "      <td>643.30</td>\n",
+       "      <td>644.30</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>19</th>\n",
+       "      <td>19</td>\n",
+       "      <td>84087</td>\n",
+       "      <td>84761</td>\n",
+       "      <td>0.186658</td>\n",
+       "      <td>558.94</td>\n",
+       "      <td>0</td>\n",
+       "      <td>558.44</td>\n",
+       "      <td>559.44</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>20</th>\n",
+       "      <td>20</td>\n",
+       "      <td>84761</td>\n",
+       "      <td>85652</td>\n",
+       "      <td>0.200695</td>\n",
+       "      <td>725.14</td>\n",
+       "      <td>0</td>\n",
+       "      <td>724.64</td>\n",
+       "      <td>725.64</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>21</th>\n",
+       "      <td>21</td>\n",
+       "      <td>85652</td>\n",
+       "      <td>94665</td>\n",
+       "      <td>0.213673</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>22</th>\n",
+       "      <td>22</td>\n",
+       "      <td>94665</td>\n",
+       "      <td>105242</td>\n",
+       "      <td>0.216747</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>23</th>\n",
+       "      <td>23</td>\n",
+       "      <td>105242</td>\n",
+       "      <td>105821</td>\n",
+       "      <td>0.220073</td>\n",
+       "      <td>810.84</td>\n",
+       "      <td>0</td>\n",
+       "      <td>810.34</td>\n",
+       "      <td>811.34</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>24</th>\n",
+       "      <td>24</td>\n",
+       "      <td>105821</td>\n",
+       "      <td>106759</td>\n",
+       "      <td>0.232923</td>\n",
+       "      <td>837.42</td>\n",
+       "      <td>0</td>\n",
+       "      <td>836.92</td>\n",
+       "      <td>837.92</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>25</th>\n",
+       "      <td>25</td>\n",
+       "      <td>106759</td>\n",
+       "      <td>107548</td>\n",
+       "      <td>0.244745</td>\n",
+       "      <td>674.64</td>\n",
+       "      <td>0</td>\n",
+       "      <td>674.14</td>\n",
+       "      <td>675.14</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>26</th>\n",
+       "      <td>26</td>\n",
+       "      <td>107548</td>\n",
+       "      <td>108235</td>\n",
+       "      <td>0.259172</td>\n",
+       "      <td>643.74</td>\n",
+       "      <td>0</td>\n",
+       "      <td>643.24</td>\n",
+       "      <td>644.24</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>27</th>\n",
+       "      <td>27</td>\n",
+       "      <td>108235</td>\n",
+       "      <td>109100</td>\n",
+       "      <td>0.272663</td>\n",
+       "      <td>725.36</td>\n",
+       "      <td>0</td>\n",
+       "      <td>724.86</td>\n",
+       "      <td>725.86</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>28</th>\n",
+       "      <td>28</td>\n",
+       "      <td>109100</td>\n",
+       "      <td>119764</td>\n",
+       "      <td>0.285483</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>29</th>\n",
+       "      <td>29</td>\n",
+       "      <td>119764</td>\n",
+       "      <td>133663</td>\n",
+       "      <td>0.288898</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>30</th>\n",
+       "      <td>30</td>\n",
+       "      <td>133663</td>\n",
+       "      <td>134601</td>\n",
+       "      <td>0.303703</td>\n",
+       "      <td>837.39</td>\n",
+       "      <td>0</td>\n",
+       "      <td>836.89</td>\n",
+       "      <td>837.89</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>31</th>\n",
+       "      <td>31</td>\n",
+       "      <td>134601</td>\n",
+       "      <td>135254</td>\n",
+       "      <td>0.315650</td>\n",
+       "      <td>643.80</td>\n",
+       "      <td>0</td>\n",
+       "      <td>643.30</td>\n",
+       "      <td>644.30</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>32</th>\n",
+       "      <td>32</td>\n",
+       "      <td>135254</td>\n",
+       "      <td>135956</td>\n",
+       "      <td>0.328527</td>\n",
+       "      <td>558.75</td>\n",
+       "      <td>0</td>\n",
+       "      <td>558.25</td>\n",
+       "      <td>559.25</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>33</th>\n",
+       "      <td>33</td>\n",
+       "      <td>135956</td>\n",
+       "      <td>136543</td>\n",
+       "      <td>0.342915</td>\n",
+       "      <td>882.45</td>\n",
+       "      <td>0</td>\n",
+       "      <td>881.95</td>\n",
+       "      <td>882.95</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>34</th>\n",
+       "      <td>34</td>\n",
+       "      <td>136543</td>\n",
+       "      <td>145312</td>\n",
+       "      <td>0.358558</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>35</th>\n",
+       "      <td>35</td>\n",
+       "      <td>145312</td>\n",
+       "      <td>156612</td>\n",
+       "      <td>0.361428</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>36</th>\n",
+       "      <td>36</td>\n",
+       "      <td>156612</td>\n",
+       "      <td>157184</td>\n",
+       "      <td>0.364755</td>\n",
+       "      <td>810.73</td>\n",
+       "      <td>0</td>\n",
+       "      <td>810.23</td>\n",
+       "      <td>811.23</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>37</th>\n",
+       "      <td>37</td>\n",
+       "      <td>157184</td>\n",
+       "      <td>158248</td>\n",
+       "      <td>0.376578</td>\n",
+       "      <td>837.35</td>\n",
+       "      <td>0</td>\n",
+       "      <td>836.85</td>\n",
+       "      <td>837.85</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>38</th>\n",
+       "      <td>38</td>\n",
+       "      <td>158248</td>\n",
+       "      <td>158901</td>\n",
+       "      <td>0.388673</td>\n",
+       "      <td>643.73</td>\n",
+       "      <td>0</td>\n",
+       "      <td>643.23</td>\n",
+       "      <td>644.23</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>39</th>\n",
+       "      <td>39</td>\n",
+       "      <td>158901</td>\n",
+       "      <td>159776</td>\n",
+       "      <td>0.401962</td>\n",
+       "      <td>725.68</td>\n",
+       "      <td>0</td>\n",
+       "      <td>725.18</td>\n",
+       "      <td>726.18</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>40</th>\n",
+       "      <td>40</td>\n",
+       "      <td>159776</td>\n",
+       "      <td>160530</td>\n",
+       "      <td>0.415132</td>\n",
+       "      <td>674.70</td>\n",
+       "      <td>0</td>\n",
+       "      <td>674.20</td>\n",
+       "      <td>675.20</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>41</th>\n",
+       "      <td>41</td>\n",
+       "      <td>160530</td>\n",
+       "      <td>178264</td>\n",
+       "      <td>0.428483</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>42</th>\n",
+       "      <td>42</td>\n",
+       "      <td>178264</td>\n",
+       "      <td>193614</td>\n",
+       "      <td>0.433222</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>0</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>-1.00</td>\n",
+       "      <td>1</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>43</th>\n",
+       "      <td>43</td>\n",
+       "      <td>193614</td>\n",
+       "      <td>194225</td>\n",
+       "      <td>0.436567</td>\n",
+       "      <td>810.82</td>\n",
+       "      <td>0</td>\n",
+       "      <td>810.32</td>\n",
+       "      <td>811.32</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>44</th>\n",
+       "      <td>44</td>\n",
+       "      <td>194225</td>\n",
+       "      <td>195235</td>\n",
+       "      <td>0.448320</td>\n",
+       "      <td>837.78</td>\n",
+       "      <td>0</td>\n",
+       "      <td>837.28</td>\n",
+       "      <td>838.28</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>45</th>\n",
+       "      <td>45</td>\n",
+       "      <td>195235</td>\n",
+       "      <td>195948</td>\n",
+       "      <td>0.460565</td>\n",
+       "      <td>674.84</td>\n",
+       "      <td>0</td>\n",
+       "      <td>674.34</td>\n",
+       "      <td>675.34</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>46</th>\n",
+       "      <td>46</td>\n",
+       "      <td>195948</td>\n",
+       "      <td>196607</td>\n",
+       "      <td>0.473103</td>\n",
+       "      <td>558.90</td>\n",
+       "      <td>0</td>\n",
+       "      <td>558.40</td>\n",
+       "      <td>559.40</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>47</th>\n",
+       "      <td>47</td>\n",
+       "      <td>196607</td>\n",
+       "      <td>197243</td>\n",
+       "      <td>0.487237</td>\n",
+       "      <td>882.54</td>\n",
+       "      <td>0</td>\n",
+       "      <td>882.04</td>\n",
+       "      <td>883.04</td>\n",
+       "      <td>2</td>\n",
+       "    </tr>\n",
+       "  </tbody>\n",
+       "</table>\n",
+       "</div>"
+      ],
+      "text/plain": [
+       "    spec_idx  peak_start_idx  peak_stop_idx        rt  precursor_mz  \\\n",
+       "0          0               0          10739  0.004935         -1.00   \n",
+       "1          1           10739          25554  0.007897         -1.00   \n",
+       "2          2           25554          26039  0.011218        810.79   \n",
+       "3          3           26039          27045  0.022838        837.34   \n",
+       "4          4           27045          27882  0.034925        725.36   \n",
+       "5          5           27882          28532  0.048620        558.87   \n",
+       "6          6           28532          29294  0.061923        812.33   \n",
+       "7          7           29294          37374  0.075015         -1.00   \n",
+       "8          8           37374          54285  0.077788         -1.00   \n",
+       "9          9           54285          54837  0.081203        810.75   \n",
+       "10        10           54837          55778  0.092903        837.96   \n",
+       "11        11           55778          56413  0.104803        644.06   \n",
+       "12        12           56413          57205  0.117215        725.23   \n",
+       "13        13           57205          57874  0.130022        559.19   \n",
+       "14        14           57874          66994  0.143452         -1.00   \n",
+       "15        15           66994          81922  0.146408         -1.00   \n",
+       "16        16           81922          82501  0.149755        811.41   \n",
+       "17        17           82501          83417  0.161442        837.36   \n",
+       "18        18           83417          84087  0.173370        643.80   \n",
+       "19        19           84087          84761  0.186658        558.94   \n",
+       "20        20           84761          85652  0.200695        725.14   \n",
+       "21        21           85652          94665  0.213673         -1.00   \n",
+       "22        22           94665         105242  0.216747         -1.00   \n",
+       "23        23          105242         105821  0.220073        810.84   \n",
+       "24        24          105821         106759  0.232923        837.42   \n",
+       "25        25          106759         107548  0.244745        674.64   \n",
+       "26        26          107548         108235  0.259172        643.74   \n",
+       "27        27          108235         109100  0.272663        725.36   \n",
+       "28        28          109100         119764  0.285483         -1.00   \n",
+       "29        29          119764         133663  0.288898         -1.00   \n",
+       "30        30          133663         134601  0.303703        837.39   \n",
+       "31        31          134601         135254  0.315650        643.80   \n",
+       "32        32          135254         135956  0.328527        558.75   \n",
+       "33        33          135956         136543  0.342915        882.45   \n",
+       "34        34          136543         145312  0.358558         -1.00   \n",
+       "35        35          145312         156612  0.361428         -1.00   \n",
+       "36        36          156612         157184  0.364755        810.73   \n",
+       "37        37          157184         158248  0.376578        837.35   \n",
+       "38        38          158248         158901  0.388673        643.73   \n",
+       "39        39          158901         159776  0.401962        725.68   \n",
+       "40        40          159776         160530  0.415132        674.70   \n",
+       "41        41          160530         178264  0.428483         -1.00   \n",
+       "42        42          178264         193614  0.433222         -1.00   \n",
+       "43        43          193614         194225  0.436567        810.82   \n",
+       "44        44          194225         195235  0.448320        837.78   \n",
+       "45        45          195235         195948  0.460565        674.84   \n",
+       "46        46          195948         196607  0.473103        558.90   \n",
+       "47        47          196607         197243  0.487237        882.54   \n",
+       "\n",
+       "    precursor_charge  isolation_lower_mz  isolation_upper_mz  ms_level  \n",
+       "0                  0               -1.00               -1.00         1  \n",
+       "1                  0               -1.00               -1.00         1  \n",
+       "2                  0              810.29              811.29         2  \n",
+       "3                  0              836.84              837.84         2  \n",
+       "4                  0              724.86              725.86         2  \n",
+       "5                  0              558.37              559.37         2  \n",
+       "6                  0              811.83              812.83         2  \n",
+       "7                  0               -1.00               -1.00         1  \n",
+       "8                  0               -1.00               -1.00         1  \n",
+       "9                  0              810.25              811.25         2  \n",
+       "10                 0              837.46              838.46         2  \n",
+       "11                 0              643.56              644.56         2  \n",
+       "12                 0              724.73              725.73         2  \n",
+       "13                 0              558.69              559.69         2  \n",
+       "14                 0               -1.00               -1.00         1  \n",
+       "15                 0               -1.00               -1.00         1  \n",
+       "16                 0              810.91              811.91         2  \n",
+       "17                 0              836.86              837.86         2  \n",
+       "18                 0              643.30              644.30         2  \n",
+       "19                 0              558.44              559.44         2  \n",
+       "20                 0              724.64              725.64         2  \n",
+       "21                 0               -1.00               -1.00         1  \n",
+       "22                 0               -1.00               -1.00         1  \n",
+       "23                 0              810.34              811.34         2  \n",
+       "24                 0              836.92              837.92         2  \n",
+       "25                 0              674.14              675.14         2  \n",
+       "26                 0              643.24              644.24         2  \n",
+       "27                 0              724.86              725.86         2  \n",
+       "28                 0               -1.00               -1.00         1  \n",
+       "29                 0               -1.00               -1.00         1  \n",
+       "30                 0              836.89              837.89         2  \n",
+       "31                 0              643.30              644.30         2  \n",
+       "32                 0              558.25              559.25         2  \n",
+       "33                 0              881.95              882.95         2  \n",
+       "34                 0               -1.00               -1.00         1  \n",
+       "35                 0               -1.00               -1.00         1  \n",
+       "36                 0              810.23              811.23         2  \n",
+       "37                 0              836.85              837.85         2  \n",
+       "38                 0              643.23              644.23         2  \n",
+       "39                 0              725.18              726.18         2  \n",
+       "40                 0              674.20              675.20         2  \n",
+       "41                 0               -1.00               -1.00         1  \n",
+       "42                 0               -1.00               -1.00         1  \n",
+       "43                 0              810.32              811.32         2  \n",
+       "44                 0              837.28              838.28         2  \n",
+       "45                 0              674.34              675.34         2  \n",
+       "46                 0              558.40              559.40         2  \n",
+       "47                 0              882.04              883.04         2  "
+      ]
+     },
+     "execution_count": 3,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "from alpharaw.mzml import MzMLReader\n",
+    "\n",
+    "mzml_reader = MzMLReader()\n",
+    "mzml_reader.load_raw(\"../../nbs_tests/test_data/small.pwiz.1.1.mzML\")\n",
+    "mzml_reader.spectrum_df"
+   ]
+  }
+ ],
+ "metadata": {
+  "kernelspec": {
+   "display_name": "base",
+   "language": "python",
+   "name": "python3"
+  },
+  "language_info": {
+   "codemirror_mode": {
+    "name": "ipython",
+    "version": 3
+   },
+   "file_extension": ".py",
+   "mimetype": "text/x-python",
+   "name": "python",
+   "nbconvert_exporter": "python",
+   "pygments_lexer": "ipython3",
+   "version": "3.12.4"
+  }
+ },
+ "nbformat": 4,
+ "nbformat_minor": 2
+}