diff --git a/Dockerfile-obabel b/Dockerfile-obabel
index af15295..0a0afe0 100644
--- a/Dockerfile-obabel
+++ b/Dockerfile-obabel
@@ -9,7 +9,7 @@ USER root
 
 # Copy the obabel pipeline implementation into the image
 COPY src/python /opt/python-obabel
-RUN apt-get install -y --no-install-recommends python-setuptools gzip python-pip && pip install -e /opt/python-obabel
+RUN apt-get update && apt-get install -y --no-install-recommends python-setuptools gzip python-pip && pip install -e /opt/python-obabel
 # And the pip packages including pipeline-utilities and im-pipelines-utils-rdkit
 RUN pip install im-pipelines-utils==2.2.* im-pipelines-utils-rdkit==1.4.*