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Generate a QC summary report for a whole data set #5

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bdecato opened this issue Mar 28, 2017 · 0 comments
Open

Generate a QC summary report for a whole data set #5

bdecato opened this issue Mar 28, 2017 · 0 comments
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@bdecato
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bdecato commented Mar 28, 2017

Description

As a bioinformatician, I would like to generate an automated summary of methylation levels in various genomic regions of interest, in order better understand the biological system of interest.

Estimate

5

Priority

SHOULD

Notes

  • Input will be the results of Calculate average DNA methylation across regions of interest #29 run across a whole data set
  • Output should be one R Markdown webpage consisting of violin/boxplots showing the regional distribution of methylation levels in gene promoters, gene bodies, retrotransposons, and intergenic regions, etc.
  • Also useful would be a boxplot/beeswarm plot of number of CpGs covered per library

For later:

  • Another useful plot would be the counts of coverage at each CpG (just a barplot, maybe pooled across all cells, probably on a log scale)
@oneillkza oneillkza changed the title Generate Summary Generate DNA methylation by region summary plot for a whole data set Oct 20, 2017
@oneillkza oneillkza changed the title Generate DNA methylation by region summary plot for a whole data set Generate a QC summary report for a whole data set Oct 20, 2017
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