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Call Copy Number From Single-Cell DNA Methylation Data #1

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bdecato opened this issue Mar 28, 2017 · 0 comments
Open

Call Copy Number From Single-Cell DNA Methylation Data #1

bdecato opened this issue Mar 28, 2017 · 0 comments
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enhancement

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@bdecato
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bdecato commented Mar 28, 2017

Description

As a biologist, I would like to use the reads from single-cell DNA methylation data to call copy number in individual cells, in order to sex them, and to detect any copy number variations from normal.

Estimate

5 hours

Priority

COULD

Notes

  • Input: BAM files, one for each cell
  • Desired output: copy number calls, by ~5mbp bin, in some lightweight format (eg tsv), per cell
cjfang added a commit that referenced this issue Jun 27, 2017
@cjfang
Merge pull request #1 from cjfang/pool_meth
20e51bd 
Added generation of methylation bigWIGS to preprocess workflow
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@bdecato