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off_target.ui
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off_target.ui
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<?xml version="1.0" encoding="UTF-8"?>
<ui version="4.0">
<class>tolerancelineEdit</class>
<widget class="QMainWindow" name="tolerancelineEdit">
<property name="geometry">
<rect>
<x>0</x>
<y>0</y>
<width>421</width>
<height>599</height>
</rect>
</property>
<property name="font">
<font>
<pointsize>12</pointsize>
</font>
</property>
<property name="windowTitle">
<string>MainWindow</string>
</property>
<widget class="QWidget" name="centralwidget">
<layout class="QGridLayout" name="gridLayout_2">
<item row="1" column="1">
<layout class="QGridLayout" name="gridLayout">
<item row="2" column="0" colspan="2">
<widget class="QGroupBox" name="Step1">
<property name="title">
<string>Step 1: Select References</string>
</property>
<layout class="QGridLayout" name="gridLayout_4">
<item row="2" column="1">
<widget class="QComboBox" name="EndocomboBox">
<property name="sizePolicy">
<sizepolicy hsizetype="Expanding" vsizetype="Fixed">
<horstretch>0</horstretch>
<verstretch>0</verstretch>
</sizepolicy>
</property>
</widget>
</item>
<item row="1" column="0">
<widget class="QLabel" name="label_2">
<property name="toolTip">
<string><html><head/><body><p><span style=" font-size:12pt;">This is the reference organism that off-target will be ran against. List is populated based on currenet CSPR files in CASPER database directory.</span></p></body></html></string>
</property>
<property name="text">
<string>Organism:</string>
</property>
</widget>
</item>
<item row="1" column="1">
<widget class="QComboBox" name="OrgcomboBox">
<property name="sizePolicy">
<sizepolicy hsizetype="Expanding" vsizetype="Fixed">
<horstretch>0</horstretch>
<verstretch>0</verstretch>
</sizepolicy>
</property>
</widget>
</item>
<item row="0" column="0" colspan="2">
<spacer name="verticalSpacer_3">
<property name="orientation">
<enum>Qt::Vertical</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Preferred</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>10</height>
</size>
</property>
</spacer>
</item>
<item row="2" column="0">
<widget class="QLabel" name="label_3">
<property name="toolTip">
<string><html><head/><body><p><span style=" font-size:12pt;">This is the reference endonuclease that will be used for off-target analysis.</span></p></body></html></string>
</property>
<property name="text">
<string>Endonuclease:</string>
</property>
</widget>
</item>
<item row="3" column="0" colspan="2">
<spacer name="verticalSpacer_7">
<property name="orientation">
<enum>Qt::Vertical</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Preferred</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>10</height>
</size>
</property>
</spacer>
</item>
</layout>
</widget>
</item>
<item row="3" column="0" colspan="2">
<widget class="QGroupBox" name="Step2">
<property name="title">
<string>Step 2: Set Parameters</string>
</property>
<layout class="QGridLayout" name="gridLayout_5">
<item row="4" column="2">
<widget class="QLineEdit" name="FileName">
<property name="text">
<string/>
</property>
<property name="placeholderText">
<string/>
</property>
</widget>
</item>
<item row="3" column="2">
<widget class="QCheckBox" name="AVG">
<property name="text">
<string/>
</property>
</widget>
</item>
<item row="2" column="0">
<widget class="QLabel" name="label_5">
<property name="toolTip">
<string><html><head/><body><p>If the number of mismatches in a putative off-target site exceeds this number, CASPER will not score the site. Computational time increases as this number increases.</p></body></html></string>
</property>
<property name="text">
<string>Max No. Mismatches:</string>
</property>
</widget>
</item>
<item row="3" column="0">
<widget class="QLabel" name="label_6">
<property name="toolTip">
<string><html><head/><body><p>Check this option if you only want to see the average off-target score for each gRNA. Leaving this option unchecked will report the average off-target score as well as the putatitve off-target sequences, their locations, and individual off-target scores.</p></body></html></string>
</property>
<property name="text">
<string>Average Output</string>
</property>
</widget>
</item>
<item row="2" column="2">
<widget class="QComboBox" name="mismatchcomboBox"/>
</item>
<item row="0" column="0" colspan="3">
<spacer name="verticalSpacer_4">
<property name="orientation">
<enum>Qt::Vertical</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Preferred</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>10</height>
</size>
</property>
</spacer>
</item>
<item row="4" column="0">
<widget class="QLabel" name="label">
<property name="text">
<string>Output File Name:</string>
</property>
</widget>
</item>
<item row="1" column="2">
<widget class="QDoubleSpinBox" name="toleranceSpinBox">
<property name="maximum">
<double>0.500000000000000</double>
</property>
<property name="singleStep">
<double>0.050000000000000</double>
</property>
<property name="value">
<double>0.050000000000000</double>
</property>
</widget>
</item>
<item row="1" column="0">
<widget class="QLabel" name="label_4">
<property name="toolTip">
<string><html><head/><body><p>Potential off-target sites scoring lower than this value are dismissed (I.e. they do not pose a threat for off-target activity). Computational time increases as tolerance value decreases.</p></body></html></string>
</property>
<property name="text">
<string>Tolerance:</string>
</property>
</widget>
</item>
<item row="5" column="0" colspan="3">
<spacer name="verticalSpacer_6">
<property name="orientation">
<enum>Qt::Vertical</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Preferred</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>10</height>
</size>
</property>
</spacer>
</item>
</layout>
</widget>
</item>
<item row="5" column="1" alignment="Qt::AlignRight">
<widget class="QPushButton" name="submitButton">
<property name="minimumSize">
<size>
<width>125</width>
<height>0</height>
</size>
</property>
<property name="text">
<string>Submit</string>
</property>
</widget>
</item>
<item row="1" column="0" colspan="2">
<widget class="Line" name="line">
<property name="orientation">
<enum>Qt::Horizontal</enum>
</property>
</widget>
</item>
<item row="4" column="0" colspan="2">
<widget class="QGroupBox" name="Step3">
<property name="title">
<string>Step 3: Run Off-Target</string>
</property>
<layout class="QGridLayout" name="gridLayout_6">
<item row="1" column="0">
<widget class="QPushButton" name="Run">
<property name="text">
<string>Run</string>
</property>
</widget>
</item>
<item row="3" column="0">
<widget class="QProgressBar" name="progressBar">
<property name="value">
<number>24</number>
</property>
</widget>
</item>
<item row="0" column="0">
<spacer name="verticalSpacer_5">
<property name="orientation">
<enum>Qt::Vertical</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Preferred</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>10</height>
</size>
</property>
</spacer>
</item>
<item row="4" column="0">
<spacer name="verticalSpacer_8">
<property name="orientation">
<enum>Qt::Vertical</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Preferred</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>10</height>
</size>
</property>
</spacer>
</item>
</layout>
</widget>
</item>
<item row="0" column="0" colspan="2">
<widget class="QLabel" name="title">
<property name="sizePolicy">
<sizepolicy hsizetype="Expanding" vsizetype="Fixed">
<horstretch>0</horstretch>
<verstretch>0</verstretch>
</sizepolicy>
</property>
<property name="text">
<string>Off-Target Analysis</string>
</property>
</widget>
</item>
<item row="5" column="0" alignment="Qt::AlignLeft">
<widget class="QPushButton" name="cancelButton">
<property name="minimumSize">
<size>
<width>125</width>
<height>0</height>
</size>
</property>
<property name="text">
<string>Cancel</string>
</property>
</widget>
</item>
</layout>
</item>
<item row="2" column="1">
<spacer name="verticalSpacer">
<property name="orientation">
<enum>Qt::Vertical</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Fixed</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>20</height>
</size>
</property>
</spacer>
</item>
<item row="1" column="2">
<spacer name="horizontalSpacer_2">
<property name="orientation">
<enum>Qt::Horizontal</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Fixed</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>20</height>
</size>
</property>
</spacer>
</item>
<item row="1" column="0">
<spacer name="horizontalSpacer">
<property name="orientation">
<enum>Qt::Horizontal</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Fixed</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>20</height>
</size>
</property>
</spacer>
</item>
<item row="0" column="1">
<spacer name="verticalSpacer_2">
<property name="orientation">
<enum>Qt::Vertical</enum>
</property>
<property name="sizeType">
<enum>QSizePolicy::Fixed</enum>
</property>
<property name="sizeHint" stdset="0">
<size>
<width>20</width>
<height>20</height>
</size>
</property>
</spacer>
</item>
</layout>
</widget>
<widget class="QStatusBar" name="statusbar"/>
</widget>
<resources/>
<connections/>
</ui>