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DESCRIPTION
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DESCRIPTION
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Package: KINNET
Type: Package
Title: Kinase INteraction NETwork Generation
Version: 0.4.0.9002
Authors@R: c(
person(given = c("Ali", "Sajid"),
family = "Imami",
role = c("aut", "cre"),
email = "[email protected]",
comment = c(ORCID = "0000-0003-3684-3539")),
person(given = "Khaled",
family = "Alganem",
role = c("aut"),
email = "[email protected]",
comment = c(ORCID = "0000-0003-3234-7669")),
person(given = c("Justin", "Fortune"),
family = "Creeden",
role = c("aut"),
email = "[email protected]",
comment = c(ORCID = "0000-0003-3123-8401")),
person(given = "Alex",
family = "Joyce",
role = c("aut"),
email = "[email protected]",
comment = c(ORCID = "0000-0003-0303-2481")))
Description: This package provides the functionality to process PamGene's PamChip
Data Output and generate kinase interaction networks from that.
This project uses a bayesian algorithm to generate bayesian networks for
defining dependence relationships between peptide sequences in the PamChip data.
It then uses a novel kinase assignment method to assign upstream kinases to each
peptide which is then output as a graph.
License: GPL (>= 3) | file LICENSE
Encoding: UTF-8
LazyData: true
Imports:
methods,
readr,
dplyr,
tibble,
bnlearn,
stringr,
tidyselect,
purrr,
tidyr,
Rgraphviz,
graph,
rlang,
effectsize
Depends:
R (>= 2.10)
RoxygenNote: 7.1.1
Collate:
'assign_kinases.R'
'compare_kinased_graphs.R'
'distances.R'
'equalize_kinase_graphs.R'
'filter_peptides.R'
'make_model.R'
'pamchip_data.R'
'pamchip_data_ptk.R'
'pamchip_data_stk.R'
'probability_matrix.R'
'ptk_methods.R'
'render_kinased_graph.R'
'render_reduced_kinased_graph.R'
'stk_methods.R'
'subset_data.R'
'update_probability_matrix.R'
Suggests:
testthat (>= 3.0.0)
Config/testthat/edition: 3